Results 111 to 120 of about 61,398 (311)

Free‐Breathing Magnetization Transfer Imaging of the Lung at 0.55 T Using bSTAR

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a clinically applicable method for magnetization transfer (MT) imaging of the lung at 0.55 T. Methods MT imaging of the chest was explored in healthy volunteers at 0.55 T using a self‐gated 3D half‐radial dual‐echo balanced steady‐state free precession sequence (bSTAR), a 2D multi‐slice gradient echo method (GRE) acquired in
Alexandra Braun, Grzegorz Bauman, Maurice Pradella, Jonathan Röcken, Katrin E. Hostettler, Oliver Bieri   +5 more
wiley   +1 more source

Lung Circulation Modeling: Status and Prospect [PDF]

, 2006
Mathematical modeling has been used to interpret anatomical and physiological data obtained from metabolic and hemodynamic studies aimed at investigating structure-function relationships in the vasculature of the lung, and how these relationships are ...
Audi, Said H., Clough, Anne V., Krenz, Gary S., Molthen, Robert C.   +3 more
core   +1 more source

Quantitative Imaging of Pyruvate Metabolism in a Patient With Anaplastic Thyroid Cancer

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Magnetic resonance imaging using hyperpolarized (HP) [1‐13C]‐pyruvate enables assessment of pyruvate metabolism in vivo and offers new insight into metabolic changes in response to cancer therapy. Widely used semi‐quantitative metrics of pyruvate metabolism can be affected by physiological factors that are extrinsic to intracellular ...
James A. Bankson, Joshua S. Niedzielski, Collin J. Harlan, Yunyun Chen, Christopher M. Walker, Philip L. Lorenzi, Lin Tan, Vikas Kundra, Matthew E. Merritt, Mukundan Ragavan, Dawid Schellingerhout, Renjie He, Yao Ding, Sahana Datar, Qing Wang, Christine B. Peterson, Clifton D. Fuller, Vlad C. Sandulache, Stephen Y. Lai   +18 more
wiley   +1 more source

A Novel Method for Generating a Fused Ventilation–Perfusion Map Using CT‐Derived Ventilation and FDG‐PET for Lung Functional Avoidance in Radiotherapy: A Feasibility Study

Precision Radiation Oncology, EarlyView.
This study retrospectively analyzed two types of respiratory phase CT and PET/CT images of 20 lung cancer patients. After DIR and functional grading, three lung function images were developed, and their correlations and differences were evaluated. Abstract Background Pulmonary ventilation–perfusion function plays a crucial role in both radiotherapy ...
Suyan Bi, Zhitao Dai, Xingru Sun, Wan Fatihah Binti Wan Sohaimi, Ahmad Lutfi Bin Yusoff   +4 more
wiley   +1 more source

Amentoflavone, a Preferentially TGF‐β Receptor 1 Inhibitor, Alleviates Cardiac Remodeling and Dysfunction Through Modulating the TGF‐β/Smad and MAPK Signaling Pathways

Phytotherapy Research, EarlyView.
Amentoflavone, a preferentially TGF‐ββ receptor 1 inhibitor, attenuates transverse aortic constriction (TAC)‐triggered cardiac hypertrophy, fibrosis, and dysfunction by suppressing downstream Smad and MAPK signaling cascades in cardiomyocytes and cardiac fibroblasts.
Jiangjiao Wu, Chengcheng Zhao, Xiaoping Li, Xinyi Guo, Wenjie Tan, Lu Zhou, Ye Zhang, Jianli Zhang, Shuo Zheng, Chunyu Zeng, Gengze Wu   +10 more
wiley   +1 more source

Prognostic Value of a Cardiopulmonary Exercise Testing‐Derived Summed Score in Idiopathic Pulmonary Fibrosis and Connective Tissue Disease‐Associated Interstitial Lung Disease: A Prospective Cohort Study

Respirology, EarlyView.
A cardiopulmonary exercise testing‐derived summed score effectively predicted mortality or lung transplantation risk in newly diagnosed interstitial lung disease. Higher summed scores (2–5) were associated with markedly lower event‐free survival rates.
Yu‐Lin Tsai, Kai‐Ming Chang, Chung‐Shih Chin, Chiann‐Yi Hsu, Yi‐Hsuan Yu, Yuan‐Yang Cheng, Pin‐Kuei Fu   +6 more
wiley   +1 more source

The Unpredictable Effect of Changing Cardiac Output on Hypoxemia after Acute Pulmonary Thromboembolism

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2008
Previous studies reported that the degree of hypoxemia following acute pulmonary thromboembolism (APTE) was highly variable and that its mechanism was mainly due to the creation of many high and low ventilation/perfusion (V/Q) units, as a result of the ...
John Y. C. Tsang, Wayne J. E. Lamm, Blazej Neradilek, Nayak L. Polissar, Michael P. Hlastala   +4 more
doaj   +1 more source

Robust Bioconjugated Antigens Induce Immune Responses Preventing Malaria Infection and its Transmission

Small, EarlyView.
Engineered malaria antigens enable in vivo bioconjugation to submicron biopolymer particles in E. coli. Two antigens are co‐tethered at high density and defined stoichiometry. The resulting thermostable particles elicit strong, durable antibody and T‐cell responses, conferring robust protection and blocking mosquito transmission.
Nivethika Sivakumaran, Yevel Flores‐Garcia, Chanel M. Naar, Shuxiong Chen, Mili Mehta, Fijs W. B. van Leeuwen, Abhai Tripathi, Rajagopal Murugan, Meta Roestenberg, Fidel Zavala, Bernd H. A. Rehm   +10 more
wiley   +1 more source

Ponto ótimo cardiorrespiratório: uma variável submáxima do teste cardiopulmonar de exercício Cardiorespiratory optimal point: a submaximal variable of the cardiopulmonary exercise testing

Arquivos Brasileiros de Cardiologia, 2012
FUNDAMENTO: No Teste Cardiopulmonar de Exercício (TCPE) máximo são analisadas diversas variáveis ventilatórias, incluindo o equivalente ventilatório de oxigênio (VE/VO2). O valor mínimo do VE/VO2 reflete a melhor integração entre os sistemas respiratório
Plínio Santos Ramos, Djalma Rabelo Ricardo, Claudio Gil Soares de Araújo   +2 more
doaj  

Preclinical Toxicity Screening of Sodium Dodecanoyloxybenzenesulfonate (LOBS) as a New Alternative Biocide Using In Vitro and In Vivo Models

Environmental Toxicology, EarlyView.
ABSTRACT Sodium hypochlorite is a well‐established biocide extensively used in both living and industrial environments; however, exposure to it or improper handling can harm the human body and the environment. Thus, safer alternatives to sodium hypochlorite are required.
Seung Eui Min, Seunghee Oh, Min Seong Jang, Kang‐Hyun Han   +3 more
wiley   +1 more source