Results 141 to 150 of about 61,398 (311)

The effect of perioperative erythropoietin‐stimulating agents and intravenous iron on patient outcomes following solid organ transplantation: A systematic review

open access: yesTransfusion Medicine, EarlyView.
Abstract Solid organ transplant is associated with high rates of anaemia and transfusion, but there is little comparative data on interventions such as erythropoietin‐stimulating agents (ESAs) and intravenous (IV) iron. We conducted a systematic review examining the association of ESAs and IV iron with outcomes in adults undergoing solid organ ...
Frank Lee   +13 more
wiley   +1 more source

Evidence-based Approach to Establish Space Suit Carbon Dioxide Limits [PDF]

open access: yes
A literature survey was conducted to assess if published data (evidence) could help inform a space suit carbon dioxide (CO2) limit. The search identified more than 120 documents about human interaction with elevated CO2. Until now, the guiding philosophy
Abercromby, Andrew F. J.   +4 more
core   +1 more source

Whole blood resuscitation and post‐traumatic organ dysfunction in injured children

open access: yesTransfusion, EarlyView.
Abstract Background Both whole blood (WB) and component therapy (CT) are used for hemostatic resuscitation in injured children. We hypothesize that early WB transfusion compared to CT alone is associated with decreased post‐traumatic organ dysfunction.
Erin V. Feeney   +7 more
wiley   +1 more source

Heart-Lung Interactions in Aerospace Medicine [PDF]

open access: yes
Few of the heart-lung interactions that are discussed have been studied in any detail in the aerospace environment, but is seems that many such interactions must occur in the setting of altered accelerative loadings and pressure breathing.
Guy, Harold J. B., Prisk, Gordon Kim
core   +1 more source

Exercise‐induced dynamic hyperinflation in chronic obstructive pulmonary disease

open access: yesExperimental Physiology, EarlyView.
Abstract Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease caused by inhalation of noxious particles, most commonly cigarette smoking. The consequent changes in airways, lung parenchyma and pulmonary vasculature lead to increased resistive, elastic and threshold loads and impaired capacity of the respiratory muscle pump. COPD
Rebecca F. D'Cruz   +2 more
wiley   +1 more source

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

open access: yesExperimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr   +2 more
wiley   +1 more source

Regional changes in cerebral blood flow between the upright and supine posture and over 3 days of bed rest

open access: yesExperimental Physiology, EarlyView.
Abstract A reduction in cerebral blood flow (CBF) has been observed during spaceflight and bed rest. We aimed to examine the magnitude and regional heterogeneity of the decrease in CBF during bed rest compared to posture changes on Earth. Seventeen participants (age, 29 ± 9 years, 7 females) were studied in the upright and supine posture and over 3 ...
Carmen Possnig   +8 more
wiley   +1 more source

Jumping on the moon as a potential exercise countermeasure

open access: yesExperimental Physiology, EarlyView.
Abstract The Moon's gravitational field strength (17% Earth's gravity) may facilitate the use of bodyweight jumping as an exercise countermeasure against musculoskeletal and cardiovascular deconditioning in reduced gravity settings. The present study characterised the acute physiological and kinetic responses to bodyweight jumping in simulated Lunar ...
Patrick Swain   +4 more
wiley   +1 more source

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