Results 21 to 30 of about 37,236 (267)

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Comparison of phase-resolved functional lung (PREFUL) MRI derived perfusion and ventilation parameters at 1.5T and 3T in healthy volunteers.

PLoS ONE, 2020
PurposeThe purpose of this study is to evaluate the influence of different field strengths on perfusion and ventilation parameters, SNR and CNR derived by PREFUL MRI using predefined sequence parameters.MethodsData sets of free breathing 2d FLASH lung ...
Julian Glandorf, Filip Klimeš, Andreas Voskrebenzev, Marcel Gutberlet, Lea Behrendt, Cristian Crisosto, Frank Wacker, Pierluigi Ciet, Jim M Wild, Jens Vogel-Claussen   +9 more
doaj   +1 more source

Optimization of anesthetic tactics in the surgical treatment of multiple primary non-small cell lung cancer

Южно-Российский онкологический журнал, 2021
The article describes a clinical case of surgical treatment of a patient with multiple primary malignant lesions of the lungs (cancer of the left lung, central peribronchial nodular tumor with involvement of the upper lobe and distal parts of the main ...
S. N. Tikhonova, D. A. Rozenko, N. D. Ushakova, N. N. Popova, A. M. Skopintsev, A. V. Shulga, I. A. Ten   +6 more
doaj   +1 more source

Measurement of continuous distributions of ventilation-perfusion ratios: theory [PDF]

Journal of Applied Physiology, 1974
The resolution of the technique considered is sufficient to describe smooth distributions containing blood flow to unventilated regions (shunt), ventilation to unperfused regions (dead space), and up to three additional modes over the range of finite ventilation-perfusion ratios.
P D, Wagner, H A, Saltzman, J B, West
openaire   +2 more sources

Relationship of ventilatory inefficiency and low cardiorespiratory fitness in the elderly: a retrospective observational study

Revista Brasileira de Geriatria e Gerontologia, 2019
Objectives : To check if ventilatory inefficiency is related to low cardiorespiratory fitness in the elderly and to identify the variable(s) of the cardiopulmonary exercise test (CPET) best suited to determining this relationship.
Murillo Frazão, Luciana Margarida de Santana Madruga França, Samarony Caio Moreno Bezerra, Paulo Eugênio Silva   +3 more
doaj   +2 more sources

Effects of PEEP on regional ventilation-perfusion mismatch in the acute respiratory distress syndrome

Critical Care, 2022
Purpose In the acute respiratory distress syndrome (ARDS), decreasing Ventilation-Perfusion $$\left( {{{\dot{V}} \mathord{\left/ {\vphantom {{\dot{V}} {\dot{Q}}}} \right.
Bertrand Pavlovsky, Antonio Pesenti, Elena Spinelli, Gaetano Scaramuzzo, Ines Marongiu, Paola Tagliabue, Savino Spadaro, Giacomo Grasselli, Alain Mercat, Tommaso Mauri   +9 more
doaj   +1 more source

Multiparametric MRI for organ quality assessment in a porcine Ex-Vivo lung perfusion system.

PLoS ONE, 2018
IntroductionEx-vivo lung perfusion (EVLP) is an emerging technique promising an expansion of the donor pool and improvements in the outcome after lung transplantation.
Julius Renne, Marcel Gutberlet, Andreas Voskrebenzev, Agilo Kern, Till Kaireit, Jan Hinrichs, Patrick Zardo, Gregor Warnecke, Marcus Krüger, Peter Braubach, Danny Jonigk, Axel Haverich, Frank Wacker, Jens Vogel-Claussen, Norman Zinne   +14 more
doaj   +1 more source

In vivo MR imaging of pulmonary perfusion and gas exchange in rats via continuous extracorporeal infusion of hyperpolarized 129Xe. [PDF]

PLoS ONE, 2012
Hyperpolarized (HP) (129)Xe magnetic resonance imaging (MRI) permits high resolution, regional visualization of pulmonary ventilation. Additionally, its reasonably high solubility (>10%) and large chemical shift range (>200 ppm) in tissues allow HP (129 ...
Zackary I Cleveland, Harald E Möller, Laurence W Hedlund, John C Nouls, Matthew S Freeman, Yi Qi, Bastiaan Driehuys   +6 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Difference in the value of arterial and end-tidal carbon dioxide tension according to different surgical positions: Does it reliably reflect ventilation-perfusion mismatch? [PDF]

Korean Journal of Anesthesiology, 2012
BackgroundBody posture, as a gravitational factor, has a clear impact on pulmonary ventilation and perfusion. In lung units with mismatched ventilation and perfusion, gas exchange and/or elimination of carbon dioxide can be impaired.
Jin Joo, Young Hee Kim, Jaemin Lee, Jong Ho Choi   +3 more
doaj   +1 more source