Results 41 to 50 of about 36,822 (219)

Deresuscitation Informed by Ultrasound in Patients with Septic Shock Trial

Journal of Ultrasound in Medicine, EarlyView.
Objectives The venous excess ultrasound (VExUS) can be used at the point‐of‐care to identify venous overload and end‐organ congestion in an effort to individually tailor resuscitation and deresuscitation in patients with septic shock. Methods We conducted a pilot randomized controlled feasibility trial of VExUS‐guided fluid management in adult patients
Brendan Innes, Christopher Allison, Nicholas Seidler, Burton Shen, Andrew Fried, Gary Phillips, Andrew Levinson, Adeel Abbasi   +7 more
wiley   +1 more source

Kaempferol Attenuates Myocardial Ischemia–Reperfusion Injury by Suppressing Ferroptosis via the KEAP1–Nrf2–GPX4 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therapy. In this study, we investigated whether kaempferol (KAE), a natural flavonol with antioxidative and antiinflammatory properties, could ...
Yan‐Bo Zhao, Ling‐Ling Sun, Xiao‐Hua Shen, Min Wang, Mei‐Hui Wang, Lu‐Lu Liu, Kai Zhang   +6 more
wiley   +1 more source

VQ‐Wave: A Physics‐Driven Spatiotemporal Deep Learning Approach for Noncontrast‐Enhanced Lung Ventilation and Perfusion MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a robust deep learning framework for noncontrast‐enhanced functional lung MRI, overcoming the limitations of spectral decomposition in the presence of physiological nonstationarity. Methods We introduce VQ‐Wave (Ventilation/Q‐perfusion Waveform‐based Assessment of Variable Evolutions), a physics‐driven spatiotemporal ...
Grzegorz Bauman, Pavlos Panos, Philipp Latzin, Oliver Bieri   +3 more
wiley   +1 more source

Ventilation Imaging of the Lung at 0.55T With Continuous Slice Cycling

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To propose and evaluate a novel method for pulmonary ventilation imaging, offering considerably improved SNR. Methods A continuous slice cycling (CSC) acquisition scheme is proposed to exclusively capture signal modulations from respiratory motion with increased SNR.
Andrea Leuthard, Grzegorz Bauman, Katrin E. Hostettler, Maurice Pradella, Oliver Bieri   +4 more
wiley   +1 more source

VENTILATION-PERFUSION RATIO IN NORM AND PATHOLOGY [PDF]

NAUKA MOLODYKH (Eruditio Juvenium), 2020
T.A. Miroshkina, S.A. Shustova, I.B. Ponomareva   +2 more
openaire   +1 more source

Post‐recanalization administration of rapamycin improves functional outcome and reduces infarct size in a rat model of ischemic stroke

Neuroprotection, EarlyView.
Experimental design and main findings of the study. Transient middle cerebral artery occlusion was induced for 90 min in rats, followed by intravenous administration of rapamycin or vehicle at the time of recanalization. Functional outcome (Garcia scale and adhesive removal test), magnetic resonance imaging‐based infarct volume assessment, and cerebral
Anna M. Schneider, Yvonne Couch, James Larkin, Alastair M. Buchan, Daniel J. Beard   +4 more
wiley   +1 more source

Middle Cerebral Artery Doppler and Cerebroplacental Ratio Predict Adverse Neurological Outcomes in Fetal Growth Restriction

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To assess the efficacy of middle cerebral artery (MCA) Doppler ultrasonography in predicting neurological and respiratory outcomes in fetuses with fetal growth restriction (FGR) and to establish a correlation between MCA Doppler and head circumference (HC). Method Retrospective cohort study examining singleton pregnancies affected by
Silvia Visentin, Ambrogio Pietro Londero, Giulia Lo Storto, Eugenio Ragazzi, Sabrina Salvadori, Eugenio Baraldi, Erich Cosmi   +6 more
wiley   +1 more source

Determinants of Improved Dyspnea and Exercise Tolerance With Nasal High‐Flow O2 Therapy in Fibrotic Interstitial Lung Disease: A Pilot Physiological Study

Respirology, EarlyView.
We tested the respective effect of high‐flow and supplemental O2 from nasal high‐flow O2 therapy (NHFO2) on dyspnea and exercise tolerance in fibrotic interstitial lung disease. Supplemental O2 and NHFO2 (but not high‐flow) provided improvements in these outcomes at “iso‐O2 saturation” due to reduced ventilatory requirements.
Sarah Thivent, Marylise Ginoux, Samuel Verges, Frédéric Hérengt, Mathieu Marillier   +4 more
wiley   +1 more source

Preclinical Toxicity Screening of Sodium Dodecanoyloxybenzenesulfonate (LOBS) as a New Alternative Biocide Using In Vitro and In Vivo Models

Environmental Toxicology, EarlyView.
ABSTRACT Sodium hypochlorite is a well‐established biocide extensively used in both living and industrial environments; however, exposure to it or improper handling can harm the human body and the environment. Thus, safer alternatives to sodium hypochlorite are required.
Seung Eui Min, Seunghee Oh, Min Seong Jang, Kang‐Hyun Han   +3 more
wiley   +1 more source

Microplastics and the Endocrine–Metabolic Interface: Novel Diagnostic Tools Targeting Thyroid–Adipose Axis

Environmental Toxicology, EarlyView.
ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni, Babasola Aiyeku, Marjorie Dardis Murucci, Temitope Aribigbola, Kenia Bispo, Oluwatosin Stella Olayinka, Rômulo Sperduto Dezonne, Sara Gemini Piperni, Paula Soares, Denise Pires de Carvalho, Leandro Miranda‐Alves   +10 more
wiley   +1 more source