Results 51 to 60 of about 1,080,382 (294)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Environmental test chamber for the support of learning and teaching in intelligent control [PDF]

open access: yes, 2004
The paper describes the utility of a low cost, 1 m2 by 2 m forced ventilation, micro-climate test chamber, for the support of research and teaching in mechatronics.
Taylor, C. James
core   +1 more source

Clinical practice of non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease

open access: yesRespiratory Research, 2023
Background Non-invasive ventilation (NIV) is an evidence-based treatment for acute respiratory failure in chronic obstructive pulmonary disease (COPD). However, suboptimal application of NIV in clinical practice, possibly due to poor guideline adherence,
Judith Elshof   +7 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Numerical study of variable lung ventilation strategies

open access: yes, 2015
Mechanical ventilation is used for patients with a variety of lung diseases. Traditionally, ventilators have been designed to monotonously deliver equal sized breaths.
Bagler, Ganesh   +3 more
core   +1 more source

Heating of the Natural Gas at the Gas-distributive Installation

open access: yesSelected Scientific Papers: Journal of Civil Engineering, 2012
Heating of natural gas on the gas-distributive installations is carried out for prevention of creation of gas hydrates in gas pressure controller. There are a few methods of heating of natural gas: complete heating of gas and heating of gas pressure ...
Savchenko Olena   +2 more
doaj   +1 more source

An estimation of exergy consumption paterns of energy‐intensive building service systems

open access: yesJournal of Civil Engineering and Management, 2006
This paper represents the estimation of life cycle exergy consumption for building service systems (BSS). The investigation explores public building engineering systems, which are the most energy‐intensive.
Darius BiekÅ¡a   +2 more
doaj   +1 more source

Enhancing of energetic and economic efficiency of air distribution by swirled-compact air jets

open access: yesProduction Engineering Archives, 2021
The article is devoted to solving the urgent task of increasing the efficiency of air distribution by swirled-compact air jets to ensure the normative parameters of indoor air.
Zhelykh Vasyl   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

IAQ and CFD study on the ventilation system in a chassis dynamometer room [PDF]

open access: yes, 2011
The chassis dynamometer room is one of many extensions in the automotive laboratory, UTHM, which is one of a few dynamometer rooms available in Malaysia.
Mohamed Ejledi, Alaeddin
core  

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