Results 171 to 180 of about 4,770,227 (251)

Brain strain: Blood flow and metabolism in environmental extremes

Experimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak, Damian M. Bailey, Travis D. Gibbons, Philip N. Ainslie   +3 more
wiley   +1 more source

Ventilator-Induced Lung Injury: The Unseen Challenge in Acute Respiratory Distress Syndrome Management. [PDF]

J Clin Med
Merola R, Vargas M, Battaglini D.
europepmc   +1 more source

Haemodynamic effects of selective venoconstriction with centhaquine in spontaneously breathing patients with mixed hypovolaemic‐vasodilatory shock

Experimental Physiology, EarlyView.
Abstract Circulatory shock remains difficult to manage because fluid resuscitation and catecholamines may exacerbate vascular dysfunction and tissue hypoperfusion. This prospective physiological analysis, embedded within a multicentre phase IV study, examined whether selectively targeting the venous circulation with centhaquine improves circulatory ...
Athanasios Chalkias, Aman Khanna, Krish Vaidya, Dharmesh Shah, Anil Gulati   +4 more
wiley   +1 more source

The potential risk of ventilator-induced lung injury from five different PEEP titration techniques in ARDS. [PDF]

Front Med (Lausanne)
Sutherasan Y, Songsomboon C, Gulapa K, Junhasavasdikul D, Theerawit P.   +4 more
europepmc   +1 more source

Neuromuscular fatigability with repeated exercise in hypoxia: From single‐joint paradigms to sprints

The Journal of Physiology, EarlyView.
Abstract figure legend Acute hypobaric or normobaric hypoxic exposure accelerates neuromuscular fatigability during repeated exercise. Indices of peripheral and central fatigue are not different at exhaustion in mild, moderate and severe hypoxia compared with normoxia, but task failure occurs earlier.
Luca Ruggiero, Franck Brocherie, Olivier Girard, Nathan Townsend, Chris J. McNeil, Grégoire P. Millet   +5 more
wiley   +1 more source

MiR-24 Attenuates Oxidative Stress and Mitochondrial Apoptosis in Ventilator-Induced Lung Injury by Targeting Bcl-2-related Ovarian Killer. [PDF]

Pulm Circ
Xu W, Ren W, Zhang L, Wang B, Gao L, Yuan D.   +5 more
europepmc   +1 more source

Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities

The Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley   +1 more source

Extracellular vesicle release in an experimental ventilator-induced lung injury porcine model. [PDF]

PLoS One
Larsson N, Claesson J, Lehtipalo S, Behndig A, Mobarrez F, Haney M.   +5 more
europepmc   +1 more source

Determinants of maximal oxygen uptake in highly trained females and males: a mechanistic study of sex differences using advanced invasive methods

The Journal of Physiology, EarlyView.
Abstract figure legend The results from this study show that maximal cardiac output, stroke volume and leg blood flow are similar between highly trained females and males after normalisation to lean body mass (LBM). However, the 10% higher haemoglobin concentration ([Hb]) and arterial O2 content in males result in higher systemic and leg O2 delivery ...
Øyvind Skattebo, Marcos Martin‐Rincon, Bjarne Rud, Joachim Nielsen, Lars Henrik N. Hegg, Andreas V. Kleive, Niels Ørtenblad, Øyvind Sandbakk, Robert Boushel, Hans‐Christer Holmberg, Jose A.L. Calbet, Jostein Hallén   +11 more
wiley   +1 more source

TRPV4 in ventilator-induced lung injury mechanisms of endothelial mechanotransduction and barrier regulation in the lung

, 2016
Michalick, Laura 1985-
core