Results 51 to 60 of about 132,279 (268)

Triggering of the Ventilator in Patient-Ventilator Interactions [PDF]

Respiratory Care, 2011
With current ventilator triggering design, in initiating ventilator breaths patient effort is only a small fraction of the total effort expended to overcome the inspiratory load. Similarly, advances in ventilator pressure or flow delivery and inspiratory flow termination improve patient effort or inspiratory muscle work during mechanical ventilation ...
openaire   +2 more sources

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper, Annaliis Lehto, Nina Nordmann, Oliver Peters, Julian Hellmann, Josef Priller, Eike Jakob Spruth, Gabor C. Petzold, Ina Vogt, Patrick Weydt, Sarah Bernsen, Elisabeth Dinter, Björn Falkenburger, René Günther, Emrah Düzel, Wenzel Glanz, Matthis Synofzik, Lukas Beichert, Annika Spottke, Michael Wagner, Frederic Brosseron, Matthias C. Schmid, Anja Schneider, Stefan Teipel, Johannes Prudlo, Andreas Hermann   +25 more
wiley   +1 more source

Precision-Controlled Bionic Lung Simulator for Dynamic Respiration Simulation

Bioengineering
Mechanical ventilation is indispensable for patients with severe respiratory conditions, and high-fidelity lung simulators play a pivotal role in ventilator testing, clinical training, and respiratory research.
Rong-Heng Zhao, Shuai Ren, Yan Shi, Mao-Lin Cai, Tao Wang, Zu-Jin Luo   +5 more
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Development and Prototyping of Oxygen Analyzer

Engineering Proceedings
In the context of developing countries, medical instruments are imported from foreign countries. To overcome this challenge, herein the design of an oxygen analyzer using ultrasonic flow sensor technology and a microcontroller while promoting local ...
Bidheyak Pokharel, Deepa Beeta Thiyam, Sachin Devkota, Devanand Kumar Sah   +3 more
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Adopting 3D printing technology to address medical device shortages during the pandemic: benefits, applications, and practical implementation

Cogent Engineering
3D Printing, also known as additive manufacturing, has significantly advanced medicine. It offers several benefits for producing medical components, including customization, cost-effectiveness and rapid prototyping.
Fady Alnajjar, Waleed Ahmed, Amged Elhassan, Medha Parambil   +3 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Significance of neutrophil extracellular traps and low-density granulocytes in advanced chronic kidney disease (stage 5D) cases with COVID-19

Renal Failure
Coronavirus disease 2019 (COVID-19) affected billions of individuals globally, with symptoms ranging from isolated blood clotting to severe acute hypoxemic respiratory failure requiring intensive respiratory support ventilators.
Wiwat Chancharoenthana, Supitcha Kamolratanakul, Wassawon Ariyanon, Thansita Bhunyakarnjanarat, Hailong Hu, Opas Traitanon, Asada Leelahavanichkul, Marcus J. Schultz, Claudio Ronco   +8 more
doaj   +1 more source

PENGEMBANGAN MODUL IPA TERPADU BERBASIS BERPIKIR KRITIS DENGAN TEMA VENTILATOR PADA SISWA SMP/MTs KELAS VIII

Inkuiri, 2015
Penelitian ini bertujuan untuk menganalisis: (1) karakteristik modul IPA terpadu berbasis berpikir kritis pada tema ventilator sehingga dapat digunakan sebagai sumber belajar siswa di SMP Negeri 6 Purwodadi; (2) kelayakan modul IPA terpadu berbasis ...
Yuliawati Susana, Sarwanto Sarwanto, Puguh Karyanto   +2 more
doaj   +1 more source