Results 61 to 70 of about 132,279 (268)

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

Vibration Characteristics Analysis and Structural Optimization of a Volute-Less Centrifugal Fan Frame

open access: yesApplied Sciences
This paper uses modal analysis and harmonic response analysis to study the vibration characteristics and vibration response of the frame of a volute-less centrifugal fan.
Longfei Zhou   +7 more
doaj   +1 more source

The Case of a 40‐Year‐Old Man With New‐Onset Status Epilepticus in the Setting of HIV Infection

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 40‐year‐old man from Andhra Pradesh in India, while on regular antiretroviral treatment (ART) for long‐standing HIV infection presented with a 1‐day history of new‐onset status epilepticus. CT and MRI brain showed multifocal cerebral ring lesions, some of which demonstrated characteristic ‘hole‐with‐a‐dot’ sign.
Vadde Akhil, Ramachandiran Nandhagopal
wiley   +1 more source

Ventilator circuits mechanics and ventilator compensation

open access: yesJournal of Mechanical Ventilation
Introduction Invasive mechanical ventilation usually uses a double limb circuit. However, those circuits are not standardized and usually come from different manufacturers with different lengths, diameters, compliances and resistances.
Ehab G. Daoud
doaj   +1 more source

Patient–Ventilator Interaction During Noninvasive Ventilation [PDF]

open access: yesRespiratory Care, 2011
Patient–ventilator discordance commonly occurs in patients receiving noninvasive ventilation (NIV). Unintentional leaks contribute to trigger and cycle asynchrony. Historically, ventilators designed for NIV with an intentional leak circuit compensated for unintentional leaks better than critical care ventilators.
openaire   +3 more sources

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

open access: yesArthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos   +2 more
wiley   +1 more source

Optimization Design of Centrifugal Fan Blades Based on Bézier Curve Method

open access: yesApplied Sciences
In order to improve the aerodynamic performance of the voluteless centrifugal fan, a multi-objective optimization design system was established by combining parametric modeling, experimental design, surrogate models, and optimization algorithms, with the
Jiaju Wang   +7 more
doaj   +1 more source

Strategies to prevent ventilator-associated lung injury in critically Ill patients

open access: yesIndian Journal of Respiratory Care, 2018
Life-saving mechanical ventilation (MV) induces or exacerbates a range of pulmonary pathologies, collectively known as ventilator-induced lung injury if there is evidence of direct causation (i.e., in the research laboratory).
Alex Joseph   +2 more
doaj   +1 more source

Perbedaan Pemberian Midazolam dan Ketamin Terhadap PaCO2 dan HCO3 pada Pasien dengan Ventilator

open access: yesJAI (Jurnal Anestesiologi Indonesia), 2013
Latar belakang: Sekitar 42 – 72% pasien yang dirawat di Unit Rawat Intensif (URI) diberikan sedasi. Obat yang digunakan yaitu midazolam dan ketamin, yang berbeda efeknya terhadap pembuluh darah.
Tatag Istanto   +2 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

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