Results 91 to 100 of about 12,515 (240)
Introduction: One of the major barriers to pain management is the lack of adequate scale for the assessment and diagnosis of pain in patients with no verbal response under mechanical ventilation in intensive care units.
Mehdi Heidarzadeh+5 more
doaj
Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani+4 more
wiley +1 more source
In this study, lipid nanoparticles are tracked in vivo using DNA barcodes to determine how varying drug loadings affect their delivery behaviors in mice. A cost‐effective strategy is developed for simultaneously monitoring the biodistribution of a library of lipid nanoparticles (LNPs).
Letao Xu+5 more
wiley +1 more source
Synthetic Aspects and Characterization Needs in MOF Chemistry – from Discovery to Applications
Overcoming the challenges of phase discovery, synthesis optimization and scale‐up, characterization, and computational studies is essential to accelerate the large‐scale application of MOFs. Life‐cycle analyses and techno‐economic analyses need to be performed to realistically assess their potential for industrial relevance.
Bastian Achenbach+4 more
wiley +1 more source
Development of 3D Reversible Smart Energy‐Saving Devices for Adaptive Energy Management
Smart energy‐saving devices with 3D structures operate passively and exhibit reversible solar heating and radiative cooling functions. These devices demonstrate superior performance in building thermal management through dual‐mode operation and provide an optimized 3D energy management platform applicable across various angular environments.
Ho Jun Jin+11 more
wiley +1 more source
This study fabricates highly sensitive, uniform SERS substrates scalable to wafer level. The dual‐function substrates integrate high‐density hot spots and spectral references for accurate quantitative detection, achieving 10⁻¹2 M BPE sensitivity (<5% deviation). Their application in monitoring urinary caffeine citrate for preterm infant apnea treatment
Yuanhao Jin+7 more
wiley +1 more source
Background Shortages of mechanical ventilation have become a constant problem in Emergency Departments (EDs), thereby affecting the timely deployment of medical interventions that counteract the severe health complications experienced during respiratory ...
Miguel Ortiz-Barrios+6 more
doaj +1 more source
An electrochromic device (ECD) based on a LiTaO3 (LTO) solid electrolyte is developed with a magenetron sputtering system. The LTO solid electrolyte‐based ECD demonstrates outstanding long‐term stability (less than 12% degradation after 3000 cycles) and fast response times (coloring: 4.13 s, bleaching: 6.14 s).
Seung‐Hoon Park+7 more
wiley +1 more source
A nematic liquid crystal elastomer (LCE) exhibiting dynamic laser oscillation behavior modulated by mechanical stretching and contraction is synthesized. This study investigates the influence of liquid crystal elastomer deformation characteristics on multidimensional complex microcavity laser systems.
Hongyang Zhu+4 more
wiley +1 more source
Improving the Photochemical Skeletal Enlargement of Pyridines to 1,2‐Diazepines with Isocyanates
Abstract In this work, we extend the one‐pot protocol to synthesize 1,2‐diazepines from commercially available and cheap starting materials. Capitalizing on isocyanate derivatives as activating agents, the photochemical skeletal enlargement occurs, while preserving key functional groups embedded in more than 30 substrates.
Clément Ghiazza+3 more
wiley +1 more source