Results 51 to 60 of about 29,916 (306)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Mechanical Ventilators in US Acute Care Hospitals
, 2013 Objective: The supply and distribution of mechanical ventilation capacity is of profound importance for planning for severe public health emergencies. However, the capability of US health systems to provide mechanical ventilation for children and adults ...
Rubinson, Lewis +12 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The comparison of ventilation parameters of anesthesia ventilators and ICU ventilators [PDF]
, 2018 Cílem práce bylo porovnání přesnosti dodávané ventilační podpory, hladiny PEEP a rychlosti odezvy ventilátoru na dechové úsilí modelu plic za použití synchronizovaných ventilačních režimů mezi anesteziologickými ventilátory a ventilátory používanými na ...
Kloudová Aneta
core
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Aquichan, 2018 Uso de una aplicación user-friendly para tableta en la comunicación con pacientes pediátricos sometidos a respirador artificial Uso de um aplicativo para tablet fácil de usar para comunicação com pacientes pediátricos em ventilação mecânica Objectives:
Chanita Tantacharoenrat +3 more
doaj
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Mechanical ventilator flow and pressure sensors: Does location matter?
Journal of Mechanical Ventilation, 2023 Introduction Accurate measurements of ventilatory outputs are crucial during mechanical ventilation support. These measurements are achieved through sensors that monitor parameters such as flow/volumes and pressures. External and internal flow sensors
Shane Toma, Mia Shokry, Ehab G. Daoud
doaj +1 more source