Results 61 to 70 of about 31,917 (305)

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Mechanical ventilator flow and pressure sensors: Does location matter?

open access: yesJournal of Mechanical Ventilation, 2023
Introduction Accurate measurements of ventilatory outputs are crucial during mechanical ventilation support. These measurements are achieved through sensors that monitor parameters such as flow/volumes and pressures. External and internal flow sensors
Shane Toma, Mia Shokry, Ehab G. Daoud
doaj   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer   +11 more
wiley   +1 more source

Bench-test comparison of 26 emergency and transport ventilators [PDF]

open access: yes, 2014
International audienceINTRODUCTION:Numerous emergency and transport ventilators are commercialized and new generations arise constantly. The aim of this study was to evaluate a large panel of ventilators to allow clinicians to choose a device, taking ...
Marjanovic, Nicolas   +5 more
core   +3 more sources

Are anesthesiologists and intensivists ready to fully working with domestically produced ventilators?

open access: yesВестник анестезиологии и реаниматологии
The objective was to determine the attitude of anesthesiologists and intensivists to the possibility of a complete transition to the use of domestic equipment for mechanical ventilation instead of imported ones.Materials and methods.
I. V. Shlyk   +3 more
doaj   +1 more source

A bench study of intensive-care-unit ventilators: new versus old and turbine-based versus compressed gas-based ventilators.

open access: yes, 2009
International audienceOBJECTIVE: To compare 13 commercially available, new-generation, intensive-care-unit (ICU) ventilators in terms of trigger function, pressurization capacity during pressure-support ventilation (PSV), accuracy of pressure ...
Thille, Arnaud, W.   +7 more
core   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk   +10 more
wiley   +1 more source

Adaptive Bayesian optimization for proportional derivative control in double-acting piston pump ventilators

open access: yesDiscover Applied Sciences
Respiratory pandemics have intensified the global demand for low-cost mechanical ventilators, particularly in resource-constrained settings such as low- and middle-income countries.
Cong Toai Truong   +5 more
doaj   +1 more source

: ventilators for noninvasive ventilation

open access: yes, 2008
International audienceThe aim of the present study was to evaluate the performance characteristics of all the ventilators proposed for home noninvasive positive-pressure ventilation in children in France. The ventilators (one volume-targeted, 12 pressure-
A. Clement   +13 more
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

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