Results 61 to 70 of about 26,138 (264)

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Reviving Decommissioned Ventilators How a Circular Economy Approach Can Assist in Tackling the South African Shortage of Ventilators during Covid-19

open access: yesThe Thinker, 2020
Sub-Saharan Africa bears the highest disease burden in human and economic costs, but commands less than one percent of global health expenditure (Aikins et al., 2010). Strong health systems are fundamental to maintaining good health. Difficult geography,
Katharina Gihring and Nickey Janse van Rensburg
doaj  

O uso da hiperinsuflação como recurso fisioterapêutico em unidade de terapia intensiva The use of hyperinflation as a physical therapy resource in intensive care unit

open access: yesRevista Brasileira de Terapia Intensiva, 2007
JUSTIFICATIVA E OBJETIVOS: Os pacientes ventilados mecanicamente geralmente apresentam grandes quantidades de secreção pulmonar devido à deficiência da função mucociliar e do transporte de muco.
Daniela Aires Lemes   +1 more
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

Continuous chest compressions with a simultaneous triggered ventilator in the Munich Emergency Medical Services: a case series

open access: yesGMS German Medical Science, 2019
Background: Mechanical chest compression devices are commonly used providing a constant force and frequency of chest compression during cardiopulmonary resuscitation.
Schaller, Stefan J.   +7 more
doaj   +1 more source

Demand and supply of invasive and noninvasive ventilators at the peak of the COVID‐19 outbreak in Okinawa

open access: yesJournal of General and Family Medicine, 2020
While Okinawa has been facing outbreak of the coronavirus disease 2019 (COVID‐19) pandemic, healthcare collapse should be prevented by sufficient supply of ventilators for caring the rapidly growing number of critically ill patients with COVID‐19.
Toshikazu Kuniya   +2 more
doaj   +1 more source

The Case of a 40‐Year‐Old Man With New‐Onset Status Epilepticus in the Setting of HIV Infection

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 40‐year‐old man from Andhra Pradesh in India, while on regular antiretroviral treatment (ART) for long‐standing HIV infection presented with a 1‐day history of new‐onset status epilepticus. CT and MRI brain showed multifocal cerebral ring lesions, some of which demonstrated characteristic ‘hole‐with‐a‐dot’ sign.
Vadde Akhil, Ramachandiran Nandhagopal
wiley   +1 more source

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

open access: yesArthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos   +2 more
wiley   +1 more source

Educational needs for trauma nursing based on career stage among emergency department nurses: a cross-sectional study [PDF]

open access: yesJournal of Acute Care Surgery
Purpose This study aimed to identify the priority areas of trauma nursing educational needs according to the career stages of emergency department (ED) nurses.
Dain Baik, Chiyoung Cha
doaj   +1 more source

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