Results 101 to 110 of about 778,421 (286)

Sweat lactate sensor for detecting anaerobic threshold in heart failure: a prospective clinical trial (LacS-001)

open access: yesScientific Reports
A simple method for determining the anaerobic threshold in patients with heart failure (HF) is needed. This prospective clinical trial (LacS-001) aimed to investigate the safety of a sweat lactate-monitoring sensor and the correlation between lactate ...
Yoshinori Katsumata   +21 more
doaj   +1 more source

Microfluidic Gratings for X‐Ray Phase Contrast Imaging

open access: yesAdvanced Science, EarlyView.
This work establishes a new protocol for the fabrication of X‐ray gratings that exploits the advantages of microfluidics and enables a more inexpensive, faster, and scalable production process. These X‐ray devices are fundamental for implementing X‐ray phase contrast imaging (XPCI) in laboratory and clinical settings, yet their costly and complex ...
Alessandro Rossi   +10 more
wiley   +1 more source

Prehypertension in young physically active adults: early vascular alterations and implications for exercise-intensity prescription

open access: yesFrontiers in Cardiovascular Medicine
BackgroundPrehypertension represents an early stage of vascular dysfunction and an important precursor of cardiovascular disease. It remains unclear whether early vascular alterations are already present in young, physically active adults and whether ...
Gašper Turnšek   +4 more
doaj   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

open access: yesAdvanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen   +11 more
wiley   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

open access: yesAdvanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang   +10 more
wiley   +1 more source

Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes

open access: yesJournal of the International Society of Sports Nutrition, 2018
Background Beetroot juice (BJ) is classified as a high-level supplement for improving sports performance. There is some controversy over the benefits of BJ supplementation for endurance exercise performance, especially when referring to well-trained ...
Manuel Vicente Garnacho-Castaño   +8 more
doaj   +1 more source

Synergistic Effects in Multistate Black Electro‐Thermochromic Smart Windows for Energy‐Efficient Modulation of Solar Heating

open access: yesAdvanced Science, EarlyView.
Hybrid electro‐thermochromic smart windows are developed for dynamic climate control by integrating a redox‐matched black electrochromic gel with a paraffin‐based thermochromic film. This synergistic combination enables multimodal solar modulation, where photothermal heating from the electrochromic layer triggers thermochromic activation at lower ...
Xilu Wu   +12 more
wiley   +1 more source

A Brief, Individualized Exercise Program at Intensities Below the Ventilatory Threshold Exerts Therapeutic Effects for Depression: A Pilot Study. [PDF]

open access: yesFront Behav Neurosci, 2021
Sakai Y   +14 more
europepmc   +1 more source

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