We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima +9 more
wiley +1 more source
Functional Heterogeneity within the Primate Ventral Striatum for Motivational Regulation. [PDF]
Iwaoki H +10 more
europepmc +1 more source
Structural and functional correlates of the response to deep brain stimulation at ventral capsule/ventral striatum region for treatment-resistant depression. [PDF]
Lai Y +12 more
europepmc +1 more source
Neural sensitivity to peer hierarchies: Risks for depressive symptoms for low status adolescents
Abstract Popularity is increasingly salient and impactful in adolescence, and unpopular youth are at significantly greater risk of experiencing depressive symptoms. However, adolescents can vary in their neural sensitivity to social stimuli, such that some adolescents may be more impacted by social status than others.
Jimmy Capella +6 more
wiley +1 more source
Amygdala-Ventral Striatum Functional Connectivity Underlies Craving in Gambling Disorder: A Mediating Role of Depressive Symptoms. [PDF]
Ishikawa Y +19 more
europepmc +1 more source
Parabiosis, Assembloids, Organoids (PAO)
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong +5 more
wiley +1 more source
The role of the ventral striatum in the relationship between impulsive decision-making and emotional self-regulation by cognitive reappraisal. [PDF]
Yoon YB, Jung WH.
europepmc +1 more source
Differential Contributions of Ventral Striatum Subregions to the Motivational and Hedonic Components of the Affective Processing of Reward. [PDF]
Pool ER +6 more
europepmc +1 more source
In Parkinson's disease, the death of dopamine neurons in the substantia nigra, resulting in a decrease in dopamine levels in the striatum. This leads to striatal damage through the HMGB1/RAGE/NF‐κB signaling pathway, thereby inducing motor and cognitive dysfunction.
Yaofeng Zhu +7 more
wiley +1 more source
Cavernoma of the left ventral striatum, anatomical and microsurgical implications of the ipsilateral transcallosal transrostral pathway. [PDF]
Leguina ABR +9 more
europepmc +1 more source

