Executive Impairment in Huntington's Disease: Insights From a Systematic Review of the Literature
Executive dysfunction in Huntington's disease follows a selective, stage‐dependent pattern, with early deficits in psychomotor speed, cognitive flexibility, inhibition, and working‐memory updating. Progression is associated with broader impairments in planning and attention.
Simone Migliore +4 more
wiley +1 more source
A brief child-friendly reward task reliably activates the ventral striatum in two samples of socioeconomically diverse youth. [PDF]
Peckins MK +9 more
europepmc +1 more source
Pubertal Hormones and the Early Adolescent Female Brain: A Multimodality Brain MRI Study
A multimodal analysis with cross‐validation was employed to examine the associations between pubertal hormones (oestradiol, testosterone, and dehydroepiandrosterone) and brain structure and function in early adolescent females. The findings indicate both unique and overlapping neural correlates of these hormones.
Muskan Khetan +6 more
wiley +1 more source
Directing negative emotional states through parallel genetically-distinct basolateral amygdala pathways to ventral striatum subregions. [PDF]
Sniffen SE +13 more
europepmc +1 more source
Relationship of ventral striatum activation during effort discounting to clinical amotivation severity in schizophrenia. [PDF]
Prettyman GE +9 more
europepmc +1 more source
Pharmacological MRI: Utility in Understanding Drug Mechanisms in Psychiatric Disorders
ABSTRACT Pharmacological MRI (pharmaMRI) has emerged as a powerful tool to study how psychoactive drugs affect brain function and to uncover mechanisms of drug action in psychiatric disorders. This review provides an overview of key techniques used in pharmaMRI, including BOLD‐fMRI, arterial spin labeling (ASL), and cerebral blood volume (CBV) mapping,
Christin Y. Sander +4 more
wiley +1 more source
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Recently Abstinent Smokers Exhibit Mood-Associated Dopamine Dysfunction in the Ventral Striatum Compared to Nonsmokers: A [11C]-(+)-PHNO PET Study. [PDF]
Calakos KC +8 more
europepmc +1 more source
Abstract Background and aims Craving is a central construct across different kinds of addictive disorders, but craving assessments are highly heterogeneous. Our aim was to develop a valid, standardized and short scale for assessing subjective feelings of acute craving for different substances and addictive behaviors using the same set of items.
Stephanie Antons +6 more
wiley +1 more source
LF-DBS of the ventral striatum shortens persistence for morphine place preference and modulates BDNF expression in the hippocampus. [PDF]
Lloret-Torres ME, Barreto-Estrada JL.
europepmc +1 more source

