Exercise-Induced Adaptations to the Mouse Striatal Adenosine System
Adenosine acts as a key regulator of striatum activity, in part, through the antagonistic modulation of dopamine activity. Exercise can increase adenosine activity in the brain, which may impair dopaminergic functions in the striatum.
Ella E. Bauer +3 more
doaj +1 more source
Increased turnover of dopamine in caudate nucleus of detoxified alcoholic patients. [PDF]
A previous study of the DOPA decarboxylase substrate 6-[(18)F]fluoro-L-DOPA (FDOPA) with positron emission tomography (PET) detected no difference of the net blood-brain transfer rate (Kin(app)) between detoxified alcoholic patients and healthy controls.
Yoshitaka Kumakura +11 more
doaj +1 more source
Learning Is Bitter and Sweet in Ventral Striatum [PDF]
AbstractThe ventral striatum (VS) plays a key role in motivationally guided learning. Setlow et al. show that VS neurons encode the significance of cues associated with both aversive and rewarding outcomes and that this neural linkage develops over time in a fashion roughly paralleling the expression of learned behavior.
openaire +2 more sources
Offline ventral subiculum-ventral striatum serial communication is required for spatial memory consolidation [PDF]
AbstractThe hippocampal formation is considered essential for spatial navigation. In particular, subicular projections have been suggested to carry spatial information from the hippocampus to the ventral striatum. However, possible cross-structural communication between these two brain regions in memory formation has thus far been unknown.
Torromino, G +11 more
openaire +5 more sources
Learning Contextual Reward Expectations for Value Adaptation [PDF]
Substantial evidence indicates that subjective value is adapted to the statistics of reward expected within a given temporal context. However, how these contextual expectations are learned is poorly understood.
Chew, B. +3 more
core +2 more sources
Altered fronto-striatal fiber topography and connectivity in obsessive-compulsive disorder. [PDF]
Fronto-striatal circuits are hypothesized to be involved in the pathophysiology of obsessive-compulsive disorder (OCD). Within this circuitry, ventral frontal regions project fibers to the ventral striatum (VS) and dorsal frontal regions to the dorsal ...
Takashi Nakamae +8 more
doaj +1 more source
Role of the ventral striatum in developing anorexia nervosa [PDF]
Functional imaging data in adult patients with anorexia nervosa (AN) support a dysfunctional signal in the ventral striatum as neural signature of AN. In the present study, development of this signal was investigated with the prediction that a characteristic pattern of ventral-striatal signalling will be shown in response to cues associated with food ...
Fladung, A-K +4 more
openaire +2 more sources
What the brain 'Likes': neural correlates of providing feedback on social media. [PDF]
Evidence increasingly suggests that neural structures that respond to primary and secondary rewards are also implicated in the processing of social rewards.
Dapretto, Mirella +3 more
core +1 more source
Modulation of Resting Connectivity Between the Mesial Frontal Cortex and Basal Ganglia
Background: The mesial prefrontal cortex, cingulate cortex, and the ventral striatum are key nodes of the human mesial fronto-striatal circuit involved in decision-making and executive function and pathological disorders.
Traian Popa +13 more
doaj +1 more source
Signatures of Value Comparison in Ventral Striatum Neurons
The ventral striatum (VS), like its cortical afferents, is closely associated with processing of rewards, but the relative contributions of striatal and cortical reward systems remains unclear. Most theories posit distinct roles for these structures, despite their similarities.
Caleb E Strait +2 more
openaire +4 more sources

