Results 51 to 60 of about 313,250 (274)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source
Frontiers in Neurology, 2018 Background: Around 30% Parkinson's disease (PD) patients develop impulse control disorders (ICDs) to D2/3 dopamine agonists and, to a lesser extent, levodopa.
Alice Martini +5 more
doaj +1 more source
Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali +4 more
wiley +1 more source
Dissociable Roles of Ventral and Dorsal Striatum in Instrumental Conditioning [PDF]
Science, 2004 Instrumental conditioning studies how animals and humans choose actions appropriate to the affective structure of an environment. According to recent reinforcement learning models, two distinct components are involved: a “critic,” which learns to predict future reward, and an “actor,” which maintains information about the rewarding outcomes of actions ...
O'Doherty, J. +5 more
openaire +4 more sources
Advanced Healthcare Materials, EarlyView.Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez +8 more
wiley +1 more source
In vivo evidence of neurophysiological maturation of the human adolescent striatum
Developmental Cognitive Neuroscience, 2015 Maturation of the striatum has been posited to play a primary role in observed increases in adolescent sensation-seeking. However, evidence of neurophysiological maturation in the human adolescent striatum is limited.
Bart Larsen, Beatriz Luna
doaj +1 more source
Expectancies in decision making, reinforcement learning, and ventral striatum [PDF]
Frontiers in Neuroscience, 2010 Decisions can arise in different ways, such as from a gut feeling, doing what worked last time, or planful deliberation. Different decision-making systems are dissociable behaviorally, map onto distinct brain systems, and have different computational demands. For instance, "model-free" decision strategies use prediction errors to estimate scalar action
Matthijs A A Van Der Meer +1 more
openaire +3 more sources
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Positive Interaction of Social Comparison and Personal Responsibility for Outcomes
Frontiers in Psychology, 2012 We formulate and test a model that allows a sharp separation between social versus private and personal responsibility versus chance in the evaluation of outcomes.
Jaroslaw eGrygolec +3 more
doaj +1 more source
Deciding when to decide : time-variant sequential sampling models explain the emergence of value-based decisions in the human brain [PDF]
, 2012 The cognitive and neuronal mechanisms of perceptual decision making have been successfully linked to sequential sampling models. These models describe the decision process as a gradual accumulation of sensory evidence over time. The temporal evolution of
Rieskamp, Jörg +2 more
core +1 more source