Results 191 to 200 of about 529,220 (309)

Toward a Prospective Definition of Atrial Fibrillation-induced Cardiomyopathy. [PDF]

Arrhythm Electrophysiol Rev
Ahluwalia N, Honarbakhsh S, Hunter RJ, Petersen S, Lloyd G, Schilling RJ.   +5 more
europepmc   +1 more source

Assessment of left ventricular function

Cleveland Clinic Journal of Medicine, 1978
openaire   +2 more sources

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Surgical reconstruction of coexisting left ventricular aneurysm and pseudoaneurysm in a patient with ventricular tachycardia: a case report. [PDF]

Eur Heart J Case Rep
Solís Chávez MB, Carnero Alcázar M, Marcos-Alberca Moreno P, Vidal Martínez M, Maroto Castellanos LC.   +4 more
europepmc   +1 more source

Intelligent Soft Opto‐Magnetic Robot for Minimally Invasive Interventional Therapy

Advanced Science, EarlyView.
An intelligent soft opto‐magnetic (iSOM) robot is developed that integrates remote magnetic actuation, skin‐mimic tactile perception, and photothermal ablation in a near‐millimeter‐scale design. It enables precise intraluminal navigation and localized ablation while providing real‐time optical feedback to support safe and accurate minimally invasive ...
Jingjing Guo, Xiaoyan Guo, Jian Wei, Miaowen Jiang, Qifa Su, Xian Xia, Zhuozhou Li, Rong Cai, Jianguo Ma, Bo Fu, Ming Li, Jing Zhong, Lijun Xu, Xunming Ji   +13 more
wiley   +1 more source

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

EDTA‐Functionalized Nanoscale Metal–Organic Framework for Onco‐Cardiology via Radiochemotherapy Synergy and Spatiotemporally Matched Iron Chelation

Advanced Science, EarlyView.
Doxorubicin (DOX)‐induced cardiotoxicity is a major limitation to its broader clinical application, while cardioprotective interventions often risk reducing the anticancer efficacy of DOX. To address these challenges, this work constructs an EDTA‐functionalized metal–organic framework that enhances tumor therapy and provides efficient cardioprotection ...
Daojing Yuan, Liyang Tian, Luwen Zhuang, Yongyu Liang, Lingfei Chen, Xuetao Wang, Yanli Li, Xiyong Yu, Teng Gong   +8 more
wiley   +1 more source

Impacts of Cardiac Dyssynchrony and Resynchronisation on Cellular Metabolism and Mitochondria: Current Understanding for Future Applications. [PDF]

Arrhythm Electrophysiol Rev
Gumrai P, Wongcharoen W, Chattipakorn SC, Thonusin C, Chattipakorn N.   +4 more
europepmc   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Prevalence and Prognostic Significance of Restriction Versus Systolic Dysfunction in Patients With Transthyretin and Light Chain Cardiac Amyloidosis. [PDF]

Circ Heart Fail
Zampieri M, Biagioni G, Del Franco A, Canepa M, Porto I, Zanoletti M, Labate ME, Porcari A, Bordignon L, Merlo M, Sinagra G, Tini G, Musumeci B, Barbato E, Autore C, Biagini E, Longhi S, Sena G, Ponziani A, Saturi G, Fico V, Argirò A, Mazzoni C, Fumagalli C, Olivotto I, Perfetto F, Cappelli F.   +26 more
europepmc   +1 more source