Results 191 to 200 of about 1,014,709 (316)
BMC Cardiovascular DisordersAims To evaluate the correlation between left atrial stiffness index (LASI) and left ventricular diastolic function in patients with coronary heart disease (CHD) by Autostrain LA technique.
Yingxuan Tu +3 more
doaj +1 more source
Assessment of left ventricular function [PDF]
Cleveland Clinic Journal of Medicine, 1978 openaire +2 more sources
The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction
Advanced Science, EarlyView.Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang +8 more
wiley +1 more source
Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization
Advanced Science, EarlyView.This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim +12 more
wiley +1 more source
Advanced Science, EarlyView.The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge +16 more
wiley +1 more source
Regulatory effect of gut microbes on blood pressure
Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 513-531, December 2022., 2022 The interaction between gut microbiota and hypertension, the genera which affect the blood pressure in taxonomic level, and the commonly used treatments to hypertension based on the gut microbes were summarized in this review. The increases of Lactobacillus, etc.
Dong Yan +6 more
wiley +1 more source
Advanced Science, EarlyView.The FGF13 level is significantly downregulated in premature aging murine hearts subject to D‐galactose and Doxorubicin. FGF13 overexpression and deficiency exacerbated and alleviated Doxorubicin/D‐galactose‐induced myocardial aging characteristics and functional impairment, respectively.
Enzhao Shen +15 more
wiley +1 more source
Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 542-549, December 2022., 2022 Schematic diagram showing RHAU can bind and unwind the G4 “knots” to modulate embryonic development and post‐natal organ function. Deficiency of RHAU gives rise to embryonic lethality, impaired organogenesis and organ dysfunction. RHAU modulates Nkx2‐5 mRNA and Yap1 mRNA at the post‐transcriptional level and facilitates the transcription of c‐Kit and ...
Chensi Yang +5 more
wiley +1 more source
Contrast Agent Clearance Dynamics and Diffusion in the Mouse Brain After Ventricular Administration
Advanced Science, EarlyView.Schematic representation of contrast agent clearance by convective bulk flow from the ventricular spaces to the subarachnoid space on the ventral aspect of the brain, or by diffusion into the parenchyma across the pia‐glia or through the semi‐permeable ependyma. Abstract Fluid and solute exchange between cerebrospinal fluid (CSF) spaces and the central
Yann Decker +2 more
wiley +1 more source
Advanced Science, EarlyView.This work identifies fine‐tuning the expression of PIEZO1 as a critical molecular mechanism underlying the treatment of myocardial infarction by mechanically adapted cardiac patches, which can support the clinical translation of cardiac patch devices.
Yuwen Lu +18 more
wiley +1 more source