The Impact of Frailty on Left Ventricle Mass and Geometry in Elderly Patients with Normal Ejection Fraction: A STROBE-Compliant Cross-Sectional Study. [PDF]
Wawrzyniak S +12 more
europepmc +1 more source
Assessment of Right Ventricular Function in Left Ventricular Assist Device Candidates
S. Hayek +4 more
semanticscholar +1 more source
Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards +8 more
wiley +1 more source
Cardiac and Vascular Adaptation During Pregnancy in Asian and Caucasian Women: Insights from a Prospective Cohort Study. [PDF]
Sonaglioni A +8 more
europepmc +1 more source
Thomas C. Crawford +20 more
semanticscholar +1 more source
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra +23 more
wiley +1 more source
An unusual application of percutaneous pulmonary valve implantation in congenitally corrected transposition of the great arteries. [PDF]
Emral HG +4 more
europepmc +1 more source
Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini +24 more
wiley +1 more source
Diagnostic and prognostic value of myocardial work indices in evaluating cardiac function damage in active acromegaly patients. [PDF]
Huang R +8 more
europepmc +1 more source
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen +8 more
wiley +1 more source

