Results 201 to 210 of about 373,905 (314)

Transcatheter Versus Surgical Aortic Valve Replacement in Severe Aortic Stenosis With Reduced Left Ventricular Ejection Fraction (≤50%): A Systematic Review and Meta-Analysis of Hemodynamic and Clinical Outcomes. [PDF]

Cureus
Santa Cruz-Venegas J, Romero-N A, López-Rubio DS, Valenzuela-García AL, Barajas-Arciga BF.   +4 more
europepmc   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun, Chen Xiaoyang, Xu Jianglin, Yang Zhi, Tao Meijiao, He Jiale, Zhao Jiangfeng, Hei Xuanding, Xu Xuegong, Wang Wei, Li Chun   +10 more
wiley   +1 more source

Left and Right Heart Remodelling at 1 Year After Transcatheter Versus Surgical Aortic Valve Replacement: A Speckle-Tracking Echocardiography Study. [PDF]

Interdiscip Cardiovasc Thorac Surg
Kislitsina ON, Chris Malaisrie S, Thomas JD, An S, Whippo B, Kruse J, Sweis RN, Asgar AW, Davidson CJ, Flaherty JD, McCarthy PM, Mehta CK.   +11 more
europepmc   +1 more source

Enhancing Blood Circulation With Epsilon‐Near‐Zero (ENZ) Materials via the Far‐Infrared Window of Human Skin

Advanced Science, EarlyView.
Epsilon‐near‐zero (ENZ) silicon carbide enables a selective far‐infrared emitter spectrally aligned with the human skin window around 10 µm for wavelength‐matched thermal therapy. In 25 within‐subject trials (50 hands) monitored by laser speckle contrast imaging, SiC increases blood perfusion by 30.2% versus a broadband graphite emitter while ...
Wen‐Teng Yao, Shan‐Chiao Yang, Ming‐Feng Tsai, Hsuen‐Li Chen   +3 more
wiley   +1 more source

Left ventricular diverticulum: A case report and differential diagnosis in an asymptomatic woman. [PDF]

Radiol Case Rep
Andrea D'Arma GM, Montatore M, Masino F, Chieppa DRR, Pollice S, Panunzio AG, Bartolomucci F, Guglielmi G.   +7 more
europepmc   +1 more source

Accurately Deciphering Tissue Heterogeneity From Spatial Multi‐Modal and Multi‐Omics With STransformer

Advanced Science, EarlyView.
STransformer is a unified deep learning framework designed to seamlessly accommodate a comprehensive landscape of spatial data. By simultaneously capturing short‐range cellular interactions and tissue‐wide semantic patterns, it extracts robust representations to accurately dissect complex tissue heterogeneity.
Xingyi Li, Jialuo Xu, Gaoyuan Du, Xiangting Jia, Dongmin Zhao, Chunyan Zhou, Kexin Xiao, Jia Gu, Junnan Zhu, Xuequn Shang   +9 more
wiley   +1 more source

Exercise-Induced Hypertension Is Associated with Cardiac Remodeling in Middle-Aged Male Long-Distance Runners: A Cross-Sectional Study. [PDF]

Life (Basel)
Kim YJ, Park HS, Nam SH, Lee SE, Lee KH, Park Y, Yoon JH, Ji MY.   +7 more
europepmc   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Correlation between diastolic function and fundus vascular features in coronary heart disease. [PDF]

Int J Ophthalmol
Wang J, Wang YC, Wang L, Li QJ, Jiang J, Wang ZL.   +5 more
europepmc   +1 more source

Facile Fabrication of Low‐Impedance, Highly Conformal Epidermal Electrodes Based on Laser‐Induced Graphene–Silver Nanocomposites

Advanced Science, EarlyView.
A facile laser‐induced graphene–silver nanocomposite strategy enables ultrathin epidermal electrodes with low impedance, high conductivity, and excellent mechanical robustness. The porous LIG–Ag conductive network mechanically interlocked with SEBS provides stable, motion‐resistant biopotential monitoring, enabling high‐fidelity ECG, EMG, and EEG ...
Jiuqiang Li, Senhao Zhang, Kai Guo, Donghai Qiu, Juzhong Zhang, Hongbo Yang, Huanyu Cheng   +6 more
wiley   +1 more source