Results 211 to 220 of about 1,060,485 (348)

Clathrin Light Chain B Drives Hepatocellular Carcinoma Progression Through Dual Mechanisms: Small Extracellular Vesicle‐Mediated Angiogenesis and the NF‐κB–PCLAF Signaling Axis

Advanced Science, EarlyView.
Clathrin Light Chain B (CLTB) drives hepatocellular carcinoma progression through dual pathways: intracellularly, it activates the NF‐κB–PCLAF axis to enhance small extracellular vesicle (sEV) uptake and tumor proliferation; extracellularly, CLTB‐enriched sEVs bind SH3KBP1 to inhibit its degradation, inducing angiogenesis and vascular leakage ...
Xiaoke Sun, Junchen Guo, Ning Zhao, Guanghua Cui, Yun Bai, Meijuan Ding, Yi Xu, Yu Yang   +7 more
wiley   +1 more source

Effect of SGLT2 inhibitors on cardiac structure and function assessed by cardiac magnetic resonance: a systematic review and meta-analysis. [PDF]

Cardiovasc Diabetol
Leo I, Salerno N, Figliozzi S, Cersosimo A, Ielapi J, Stankowski K, Bisaccia G, Dellegrottaglie S, Canino G, De Rosa S, Sorrentino S, Bucciarelli-Ducci C, Torella D.   +12 more
europepmc   +1 more source

Contemporary management of acute right ventricular failure: a statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology

European Journal of Heart Failure, 2016
V. Harjola, A. Mebazaa, J. Čelutkienė, D. Bettex, H. Bueno, O. Chioncel, M. Crespo-Leiro, V. Falk, G. Filippatos, S. Gibbs, A. Leite-Moreira, Johan Lassus, J. Masip, C. Mueller, W. Mullens, R. Naeije, Anton Vonk Nordegraaf, J. Parissis, J. Riley, A. Ristic, G. Rosano, A. Rudiger, F. Ruschitzka, P. Seferovic, B. Sztrymf, A. Vieillard-Baron, M. Yılmaz, S. Konstantinides   +27 more
semanticscholar   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

Analysis of atrioventricular function and myocardial strain in hypertensive heart disease: a CMR-based study. [PDF]

Sci Rep
Niu J, Zhu J, Wang Y, Chen J, Li H, Qu Y, Li X, Sheng W, Wang S.   +8 more
europepmc   +1 more source

Rationally Designed TadA‐Derived Cytosine Editors Enable Context‐Independent Zebrafish Genome Editing

Advanced Science, EarlyView.
A next‐generation cytosine base editor (zTadCBE) and other variants are developed by combining the high‐efficiency (TadCBEa) and low‐indel (TadCBEMax) architectures, followed by the introduction of zebrafish‐optimized mutations (V82S, Q154R) in the TadA domain.
Wei Qin, Sheng‐Jia Lin, Yu Zhang, Kevin Huang, Cassidy Petree, Kevin Boyd, Pratishtha Varshney, Gaurav K. Varshney   +7 more
wiley   +1 more source

Effects of the long‐term administration of nebivolol on the clinical symptoms, exercise capacity, and left ventricular function of patients with diastolic dysfunction: results of the ELANDD study

European Journal of Heart Failure, 2012
V. Conraads, M. Metra, O. Kamp, G. D. De Keulenaer, B. Pieske, J. Zamorano, P. Vardas, M. Böhm, L. Dei Cas   +8 more
semanticscholar   +1 more source

Open Challenges and Opportunities in Piezoelectricity for Tissue Regeneration

Advanced Science, EarlyView.
This review provides an intriguing review of the recent advancements, challenges, and future perspectives regarding the application of piezoelectric scaffolds in tissue regeneration. The detailed exposition is anticipated to propel the advancement of personalized and intelligent piezoelectric implants, thereby fostering significant progress in this ...
Xiaoling Deng, Yu Zhuang, Jinjie Cui, Liyun Wang, Huilu Zhan, Xudong Wang, Kaili Lin, Changyong Yuan   +7 more
wiley   +1 more source

Causal relationships between inflammatory mediators, sleep traits, and cardiac magnetic resonance imaging-derived cardiac phenotypes. [PDF]

Sci Rep
Cao S, Xu H, Tang Y, Xu Z, Yu S.
europepmc   +1 more source

Lack of Myocardial Perfusion Immediately After Successful Thrombolysis: A Predictor of Poor Recovery of Left Ventricular Function in Anterior Myocardial Infarction

Circulation, 1992
Hiroshi Ito, Toshio Tomooka, N. Sakai, Hisahiro Yu, Y. Higashino, K. Fujii, T. Masuyama, A. Kitabatake, T. Minamino   +8 more
semanticscholar   +1 more source