Results 91 to 100 of about 40,764 (311)

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

A rare case of accessory mitral valve tissue causing left ventricular outflow tract obstruction associated with parachute mitral valve, ventricular septal defect, bicuspid aortic valve, unruptured aneurysm of aortic sinus: a case report

European Heart Journal: Case Reports, 2018
Background Accessory mitral valve tissue rarely causes left ventricular outflow tract obstruction in adults. It is often associated with other cardiac and vascular congenital malformations.
Yanan Li, Yanbin Hu, Jiaxiang Wang, Lin Liu   +3 more
semanticscholar   +1 more source

Left ventricular outflow tract obstruction by accessory mitral tissue. A review regarding a case.

Revista Cubana de Cardiología y Cirugía Cardiovascular, 2011
The presence of accessory mitral valve tissue is a rare congenital abnormality that rarely,causes left ventricular outflow tract obstruction. Its presentation in adults is uncommon.
Iovank González Artiles, Raymid García Fernández, Guillermo Mojenas Morfa, Benito Sainz González de la Peña, Luis Benito Ramos Gutiérrez, Ailema Lima Guerra   +5 more
doaj  

The Prevalence of Fabry Disease Among Turkish Patients with Non-Obstructive Hypertrophic Cardiomyopathy: Insights from a Screening Study

Balkan Medical Journal, 2019
Aims: Fabry disease is an X-linked lysosomal storage disorder due to a deficiency of the α-galactosidase A enzyme. Cardiac involvement is present in over 60% of adult cases of Fabry disease.
Hasan Ali Barman, Barış İkitimur, Burçak Kılıçkıran Avcı, Eser Durmaz, Adem Atıcı, Serkan Aslan, Serdar Ceylaner, Hakan Karpuz   +7 more
doaj   +1 more source

Lower left ventricular ejection time in MYBPC3 variant carriers with overt or subclinical hypertrophic cardiomyopathy

ESC Heart Failure, EarlyView.
Abstract Aims Hypertrophic cardiomyopathy (HCM) is an inherited cardiomyopathy often caused by pathogenic variants in MYBPC3 and MYH7, encoding myosin‐binding protein C3 and myosin heavy chain 7, respectively. These variants can cause increased actin–myosin crossbridge cycling, resulting in ventricular hypercontractility, but mice lacking Mybpc3 ...
Isabell Yan, Zoe Möhring, Daniel Reichart, Fanny Kortüm, Julia Münch, Rixa Woitschach, Paulus Kirchhof, Lucie Carrier, Carolyn Y. Ho, Thomas Eschenhagen, Monica Patten   +10 more
wiley   +1 more source

Surgical removal of a left ventricular myxoma in an infant

Annals of Pediatric Cardiology, 2013
Left ventricular (LV) myxoma is particularly rare in children and has not been reported in infants. A five-month-old baby presented with a myxoma arising from the anterior, lateral, and superior aspect of the LV, causing severe left ventricular outflow ...
Srinath N Reddy, G S Sunil, Raman Krishna Kumar   +2 more
doaj   +1 more source

The Interplay of Ontogeny and Phylogeny at the Transcriptome Level of the Tetrapod Heart

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
The main stages of development during which species‐specific heart anatomy is determined in the ontogeny of representative tetrapods. Transcriptomic similarity is expected earlier in development before heart anatomy diverges. ABSTRACT The tetrapod heart is characterized by three chambers in amphibians and non‐avian reptiles, as opposed to four in birds,
G. A. Cordero, A. K. Holloway, T. Friedrich, J. Eme, W. Eckalbar, K. Kusumi, F. J. Janzen, J. W. Hicks, F. L. Conlon, B. G. Bruneau, K. S. Pollard   +10 more
wiley   +1 more source

Refractory Hypotension after Liver Allograft Reperfusion: A Case of Dynamic Left Ventricular Outflow Tract Obstruction

Frontiers in Medicine, 2016
Hypotension after reperfusion is a common occurrence during liver transplantation following the systemic release of cold, hyperkalemic, and acidic contents of the liver allograft.
M. Essandoh, A. Otey, A. Dalia, E. Dewhirst, A. Springer, M. Henry   +5 more
semanticscholar   +1 more source

First‐Trimester Fetal Cardiac Function Measurements Using Spatio‐Temporal Image Correlation and Two Ultrasound‐Related Post‐Processing Methods: A Feasibility and Reproducibility Study

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To study the feasibility and reproducibility of two ultrasound (US) related post‐processing methods for first‐trimester fetal cardiac function assessment by ventricle volume measurements. Method First‐trimester transvaginal Spatio‐Temporal Image Correlation (STIC) US datasets acquired between 11+0–13+6 weeks gestational age (GA) were
K. Zandbergen, M. Rousian, Q. C. J. Griep, A. H. J. Koning, J. M. J. Cornette, B. R. Rebel, E. A. P. Steegers, A. G. M. G. J. Mulders   +7 more
wiley   +1 more source

Clinical impact of left ventricular outflow tract obstruction in takotsubo cardiomyopathy.

Circulation Journal, 2015
BACKGROUND A hyperdynamic state of the basal left ventricle sometimes results in obstruction of the left ventricular outflow tract (LVOT). However, the prevalence, clinical presentation, and prognostic effect of LVOT obstruction in takotsubo ...
Tetsuma Kawaji, H. Shiomi, T. Morimoto, J. Tazaki, M. Imai, Naritatsu Saito, T. Makiyama, S. Shizuta, K. Ono, Takeshi Kimura   +9 more
semanticscholar   +1 more source