Results 91 to 100 of about 61,734 (360)

Hemodynamic Effects, Safety, and Feasibility of Intravenous Esmolol Infusion During Takotsubo Cardiomyopathy With Left Ventricular Outflow Tract Obstruction: Results From A Multicenter Registry.

Cardiovascular Therapeutics, 2016
BACKGROUND Left ventricular outflow tract obstruction (LVOTO) may complicate an episode of Takotsubo cardiomyopathy (TTC), potentially leading to cardiogenic shock. Beta-blockers are considered the most suitable treatment for such complication.
F. Santoro, R. Ieva, A. Ferraretti, M. Fanelli, F. Musaico, Nicola Tarantino, L. Martino, L. Gennaro, P. Caldarola, M. Biase, N. Brunetti   +10 more
semanticscholar   +1 more source

Pharmacokinetics of a single dose of Aficamten (CK‐274) on cardiac contractility in a A31P MYBPC3 hypertrophic cardiomyopathy cat model

Journal of Veterinary Pharmacology and Therapeutics, Volume 46, Issue 1, Page 52-61, January 2023., 2023
Abstract Hypertrophic cardiomyopathy (HCM) is the most prevalent cardiac disease in cats and lacks efficacious preclinical pharmacologic intervention, prompting investigation of novel therapies. Genetic mutations encoding sarcomeric proteins are implicated in the development of HCM and small molecule myosin inhibitors are an emerging class of ...
Ashley N. Sharpe, Maureen S. Oldach, Joanna L. Kaplan, Victor Rivas, Samantha L. Kovacs, Darren T. Hwee, Bradley P. Morgan, Fady I. Malik, Samantha P. Harris, Joshua A. Stern   +9 more
wiley   +1 more source

A rule-based method to model myocardial fiber orientation in cardiac biventricular geometries with outflow tracts [PDF]

arXiv, 2018
Rule-based methods are often used for assigning fiber orientation to cardiac anatomical models. However, existing methods have been developed using data mostly from the left ventricle. As a consequence, fiber information obtained from rule-based methods often does not match histological data in other areas of the heart such as the right ventricle ...
arxiv  

Alignment of Tractography Streamlines using Deformation Transfer via Parallel Transport [PDF]

arXiv, 2021
We present a geometric framework for aligning white matter fiber tracts. By registering fiber tracts between brains, one expects to see overlap of anatomical structures that often provide meaningful comparisons across subjects. However, the geometry of white matter tracts is highly heterogeneous, and finding direct tract-correspondence across multiple ...
arxiv  

Role of Septal Myectomy in Pediatric Hypertrophic Cardiomyopathy

Kardiyovasküler Tıp E Dergisi/E Journal of Cardiovascular Medicine
Hypertrophic cardiomyopathy is a prevalent cause of sudden cardiac death among young people. This distinctive genetic condition can manifest at any age from infancy to adulthood.
Sameh M. Said
doaj   +1 more source

Metabolic changes during cardiac regeneration in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background The axolotl is a prominent model organism of heart regeneration due to its ability to anatomically and functionally repair the heart after an injury that mimics human myocardial infarction. In humans, such an injury leads to permanent scarring. Cardiac regeneration has been linked to metabolism and the oxygenation state, but so far,
Anita Dittrich, Sofie Amalie Andersson, Morten Busk, Kasper Hansen, Casper Bindzus Foldager, Johan Palmfeldt, Asger Andersen, Michael Pedersen, Mikkel Vendelbo, Kirstine Lykke Nielsen, Henrik Lauridsen   +10 more
wiley   +1 more source

Infective Endocarditis After Melody Valve Implantation in the Pulmonary Position: A Systematic Review

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Infective endocarditis (IE) after transcatheter pulmonary valve implantation (TPVI) in dysfunctioning right ventricular outflow tract conduits has evoked growing concerns.
Mohammad Abdelghani, Martina Nassif, Nico A. Blom, Martijn S. Van Mourik, Bart Straver, David R. Koolbergen, Jolanda Kluin, Jan G. Tijssen, Barbara J. M. Mulder, Berto J. Bouma, Robbert J. de Winter   +10 more
doaj   +1 more source

Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins

Developmental Dynamics, EarlyView.
Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming, Fang Liu, Hannah R. Moran, Robert L. Lalonde, Megan Adams, Nicole K. Restrepo, Parnal Joshi, Stephen C. Ekker, Karl J. Clark, Iddo Friedberg, Saulius Sumanas, Chunyue Yin, Christian Mosimann, Jeffrey J. Essner, Maura McGrail   +14 more
wiley   +1 more source

IL‐6 signaling in acute exercise and chronic training: Potential consequences for health and athletic performance

Scandinavian Journal of Medicine &Science in Sports, Volume 33, Issue 1, Page 4-19, January 2023., 2023
The cytokine interleukin‐6 (IL‐6) is involved in a diverse set of physiological processes. Traditionally, IL‐6 has been thought of in terms of its inflammatory actions during the acute phase response and in chronic conditions such as rheumatoid arthritis and obesity.
Dan Nash, Michael G. Hughes, Lee Butcher, Rebecca Aicheler, Paul Smith, Tom Cullen, Richard Webb   +6 more
wiley   +1 more source

Clinical Effect of the Modified Morrow Septal Myectomy Procedure for Biventricular Hypertrophic Cardiomyopathy

Reviews in Cardiovascular Medicine
Background: Right ventricular involvement in hypertrophic cardiomyopathy is uncommon. This study aimed to evaluate clinical outcomes of the modified septal myectomy in patients diagnosed with biventricular hypertrophic cardiomyopathy (BHCM), a subject ...
Tong Tan, Wei Zhu, Jianrui Ma, Bingqi Fu, Xiaodong Zeng, Ruobing Wang, Xiaoyi Li, Jian Liu, Jian Zhuang, Jimei Chen, Huiming Guo   +10 more
doaj   +1 more source