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Nanoparticles for Postinfarct Ventricular Remodeling [PDF]

open access: yesNanomedicine, 2018
In recent years, tremendous progress has been made in the treatment of acute myocardial infarction, but pathological ventricular remodeling often causes survivors to suffer from fatal heart failure. Currently, there is no effective therapy to attenuate ventricular remodeling.
Dong, C., Ma, A., Shang, Lijun
openaire   +4 more sources

Calcineurin Aβ gene knockdown inhibits transient outward potassium current ion channel remodeling in hypertrophic ventricular myocyte [PDF]

open access: goldOpen Life Sciences, 2021
It has been shown that the activation of calcineurin is involved in regulating ion channel remodeling in hypertrophic cardiomyocytes. But the precise role of calcineurin in the regulation of transient outward potassium current (I to), an ...
Yang Long   +7 more
doaj   +2 more sources

Comprehensive Insights into Mechanisms for Ventricular Remodeling in Right Heart Failure [PDF]

open access: yesReviews in Cardiovascular Medicine
Ventricular remodeling in right heart failure is a complex pathological process involving interactions between multiple mechanisms. Overactivation of the neuro-hormonal pathways, activation of the oxidative stress response, expression of cytokines ...
Dongmei Jiang   +3 more
doaj   +2 more sources

Roles of Autophagy, Mitophagy, and Mitochondria in Left Ventricular Remodeling after Myocardial Infarction [PDF]

open access: yesReviews in Cardiovascular Medicine
This review examines the mechanisms of left ventricular dysfunction, focusing on the interplay between ventricular remodeling, autophagy, and mitochondrial dysfunction following myocardial infarction.
Xin Zhang   +5 more
doaj   +2 more sources

Pathological Ventricular Remodeling [PDF]

open access: yesCirculation, 2013
Despite declines in heart failure morbidity and mortality with current therapies, rehospitalization rates remain distressingly high, substantially affecting individuals, society, and the economy. As a result, the need for new therapeutic advances and novel medical devices is urgent.
Jana S, Burchfield   +2 more
semanticscholar   +6 more sources

Guanxin V alleviates ventricular remodeling by promoting transforming growth factor-beta 1-mediated proteasomal degradation of Vimentin

open access: yesPoultry Science, 2023
: More and more studies have demonstrated that proteasomal degradation occurs in the development of various diseases, including ventricular remodeling, which is a cardiac pathological change and seriously makes patient outcomes worse.
Ning Gu, Bo Liang
doaj   +1 more source

Left Ventricular Remodeling after Myocardial Infarction: From Physiopathology to Treatment

open access: yesLife, 2022
Myocardial infarction (MI) is the leading cause of death and morbidity worldwide, with an incidence relatively high in developed countries and rapidly growing in developing countries.
Sabina Andreea Leancă   +7 more
semanticscholar   +1 more source

Insight into the Role of the PI3K/Akt Pathway in Ischemic Injury and Post-Infarct Left Ventricular Remodeling in Normal and Diabetic Heart

open access: yesCells, 2022
Despite the significant decline in mortality, cardiovascular diseases are still the leading cause of death worldwide. Among them, myocardial infarction (MI) seems to be the most important.
Bartosz Walkowski   +3 more
semanticscholar   +1 more source

Cellular and Molecular Mechanism of Traditional Chinese Medicine on Ventricular Remodeling

open access: yesFrontiers in Cardiovascular Medicine, 2021
Ventricular remodeling is related to the renin-angiotensin-aldosterone system, immune system, and various cytokines involved in inflammation, apoptosis, and cell signal regulation.
Yong-Chun Zhu, Bo Liang, Ning Gu
doaj   +1 more source

Left ventricular myocardial remodeling in dogs with mitral valve endocardiosis [PDF]

open access: yesVeterinary World, 2020
Background and Aim: Left ventricular myocardial remodeling could play an important role in the progression of chronic heart failure (CHF) syndrome in dogs with mitral valve endocardiosis.
Yury A. Vatnikov   +9 more
doaj   +1 more source

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