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Comprehensive Insights into Mechanisms for Ventricular Remodeling in Right Heart Failure [PDF]

open access: yesReviews in Cardiovascular Medicine
Ventricular remodeling in right heart failure is a complex pathological process involving interactions between multiple mechanisms. Overactivation of the neuro-hormonal pathways, activation of the oxidative stress response, expression of cytokines ...
Dongmei Jiang   +3 more
doaj   +2 more sources

Calcineurin Aβ gene knockdown inhibits transient outward potassium current ion channel remodeling in hypertrophic ventricular myocyte [PDF]

open access: goldOpen Life Sciences, 2021
It has been shown that the activation of calcineurin is involved in regulating ion channel remodeling in hypertrophic cardiomyocytes. But the precise role of calcineurin in the regulation of transient outward potassium current (I to), an ...
Yang Long   +7 more
doaj   +2 more sources

Roles of Autophagy, Mitophagy, and Mitochondria in Left Ventricular Remodeling after Myocardial Infarction [PDF]

open access: yesReviews in Cardiovascular Medicine
This review examines the mechanisms of left ventricular dysfunction, focusing on the interplay between ventricular remodeling, autophagy, and mitochondrial dysfunction following myocardial infarction.
Xin Zhang   +5 more
doaj   +2 more sources

Guanxin V alleviates ventricular remodeling by promoting transforming growth factor-beta 1-mediated proteasomal degradation of Vimentin

open access: yesPoultry Science, 2023
: More and more studies have demonstrated that proteasomal degradation occurs in the development of various diseases, including ventricular remodeling, which is a cardiac pathological change and seriously makes patient outcomes worse.
Ning Gu, Bo Liang
doaj   +1 more source

Evaluation of Ventricular Remodeling and Prognosis in Patients with Aortic Stenosis Who Underwent Surgical or Percutaneous Transcatheter Aortic Valve Replacement [PDF]

open access: yesBrazilian Journal of Cardiovascular Surgery, 2022
Introduction: Aortic stenosis is the most common heart valve disease in the world, and patients that present with symptoms have a high mortality rate. Aortic valve replacement has the objective of promote left ventricular remodeling, reduce symptoms, and
Rodrigo de Moura Joaquim   +3 more
doaj   +1 more source

Left ventricular myocardial remodeling in dogs with mitral valve endocardiosis [PDF]

open access: yesVeterinary World, 2020
Background and Aim: Left ventricular myocardial remodeling could play an important role in the progression of chronic heart failure (CHF) syndrome in dogs with mitral valve endocardiosis.
Yury A. Vatnikov   +9 more
doaj   +1 more source

Cellular and Molecular Mechanism of Traditional Chinese Medicine on Ventricular Remodeling

open access: yesFrontiers in Cardiovascular Medicine, 2021
Ventricular remodeling is related to the renin-angiotensin-aldosterone system, immune system, and various cytokines involved in inflammation, apoptosis, and cell signal regulation.
Yong-Chun Zhu, Bo Liang, Ning Gu
doaj   +1 more source

Clinical and echocardiographic predictors of left ventricular remodeling following anterior acute myocardial infarction

open access: yesClinics, 2021
OBJECTIVES: Coronary artery disease is the primary cause of death and is responsible for a high number of hospitalizations worldwide. Ventricular remodeling is associated with worse prognosis following ST-segment elevation myocardial infarction (STEMI ...
Caroline Ferreira da Silva Mazeto Pupo da Silveira   +10 more
doaj   +1 more source

Atrial remodeling is directly related to end-diastolic left ventricular pressure in a mouse model of ventricular pressure overload. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Atrial fibrillation (AF) is often preceded by underlying cardiac diseases causing ventricular pressure overload. OBJECTIVE: It was our aim to investigate the progression of atrial remodeling in a small animal model of ventricular pressure ...
Anne Margreet De Jong   +5 more
doaj   +1 more source

LuQi Formula relieves ventricular remodeling through improvement of HIF-1α-mediated intestinal barrier integrity

open access: yesChinese Medicine, 2023
Background Ventricular remodeling is the adaptive process in which the heart undergoes changes due to stress, leading to heart failure (HF). The progressive decline in cardiac function is considered to contribute to intestinal barrier impairment.
Jirong Yan   +11 more
doaj   +1 more source

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