Results 111 to 120 of about 1,071,989 (385)

Altered excitation-contraction coupling in human chronic atrial fibrillation [PDF]

open access: yes, 2012
This review focuses on the (mal)adaptive processes in atrial excitation-contraction coupling occurring in patients with chronic atrial fibrillation. Cellular remodeling includes shortening of the atrial action potential duration and effective refractory ...
Grandi, E., Pandit, S.V., Workman, A.J.
core   +1 more source

Computational Design and Glycoengineering of Interferon‐Lambda for Nasal Prophylaxis Against Respiratory Viruses

open access: yesAdvanced Science, EarlyView.
This study presents an engineered human interferon‐lambda (hIFN‐λ) as an intranasal prophylactic against respiratory viruses. By combining AI‐guided backbone redesign and glycoengineering, the authors developed a thermostable, protease‐resistant, and scalable variant with improved mucosal penetration.
Jeongwon Yun   +12 more
wiley   +1 more source

CLINICAL PREDICTIVE VALUE OF TISSUE INHIBITOR OF METALLOPROTEINASE-1 IMYOCARDIAL REMODELING DEVELOPMENT IN PATIENTS HAVING Q-WAVE MYOCARDIAL INFARCTION

open access: yesАтеросклероз, 2019
In this paper we thought to investigate clinical value of tissue inhibitor of metalloproteinase-1 (TIMP-1) in predicting left ventricular (LV) myocardial remodeling in patients having Q-wave myocardial infarction (Q-wave MI).
A. S. Vorobyev   +5 more
doaj   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

open access: yesAdvanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren   +9 more
wiley   +1 more source

Left ventricular assist device-induced reverse ventricular remodeling

open access: yesProgress in Cardiovascular Diseases, 2000
Left ventricular assist devices provide chronic pressure and volume unloading of the dilated left ventricle in patients with end-stage heart failure. This is associated with reverse structural remodeling (normalization of the passive pressure-volume relationship), reverse molecular remodeling (increased expression of several genes involved in calcium ...
D, Burkhoff   +4 more
openaire   +2 more sources

Prediction of Left Ventricular Remodeling after a Myocardial Infarction: Role of Myocardial Deformation: A Systematic Review and Meta-Analysis

open access: yesPLoS ONE, 2016
Aims Left ventricular (LV) adverse or reverse remodeling after ST-segment elevation myocardial infarction (MI) is the best outcome to assess the benefit of revascularization.
O. Huttin   +9 more
semanticscholar   +1 more source

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

open access: yesAdvanced Science, EarlyView.
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu   +17 more
wiley   +1 more source

The effect of rosuvastatin on inflammation, matrix turnover and left ventricular remodeling in dilated cardiomyopathy: a randomized, controlled trial.

open access: yesPLoS ONE, 2014
BackgroundDilated cardiomyopathy is characterized by left ventricular dilatation and dysfunction. Inflammation and adverse remodeling of the extracellular matrix may be involved in the pathogenesis.
Kaspar Broch   +12 more
doaj   +1 more source

Aging Impairs Reverse Remodeling and Recovery of Ventricular Function after Isoproterenol-Induced Cardiomyopathy [PDF]

open access: gold, 2021
Laia Yáñez-Bisbe   +9 more
openalex   +1 more source

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