Results 121 to 130 of about 123,523 (307)

Left Ventricular Dyssynchrony Acutely After Myocardial Infarction Predicts Left Ventricular Remodeling

, 2007
ObjectivesWe sought to identify predictors of left ventricular (LV) remodeling after acute myocardial infarction.BackgroundLeft ventricular remodeling after myocardial infarction is associated with an adverse long-term prognosis.
Bax, Jeroen J., Holman, Eduard R., Gorcsan, John, Suffoletto, Matthew S., Mollema, Sjoerd A., Bleeker, Gabe B., van der Hoeven, Bas L., Schalij, Martin J., Boersma, Eric, van der Wall, Ernst E., van de Veire, Nico R., Liem, Su San   +11 more
core   +1 more source

Resolution of Refractory Multifocal Atrial Tachycardia in Costello Syndrome Using Trametinib: A Case Supporting MEK Inhibitors as Targeted, Specific Antiarrhythmic

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Arrhythmias affect approximately half of patients with Costello syndrome (CS, OMIM # 218040), with non‐reentrant atrial tachycardia being the most common. This case describes an infant with Costello syndrome carrying the pathogenic HRAS c.34G>A (p.G12S) variant who developed early‐onset, drug‐refractory multifocal atrial tachycardia (MAT ...
Vanina Taliercio, Annabelle Wilcox, Stacey Cole, Josue Flores Daboub, José E. Morales Moreno, Kasey G. Andrews, S. Yukiko Asaki, Thomas A. Pilcher, Martin Tristani‐Firouzi, Mary C. Niu, David Viskochil, Benjamin Hammond   +11 more
wiley   +1 more source

Corrigendum: Pinocembrin Decreases Ventricular Fibrillation Susceptibility in a Rat Model of Depression

Frontiers in Pharmacology, 2021
Tianxin Ye, Tianxin Ye, Tianxin Ye, Cui Zhang, Cui Zhang, Cui Zhang, Gang Wu, Gang Wu, Gang Wu, Weiguo Wan, Weiguo Wan, Weiguo Wan, Yan Guo, Yan Guo, Yan Guo, Yuhong Fo, Yuhong Fo, Yuhong Fo, Xiuhuan Chen, Xiuhuan Chen, Xiuhuan Chen, Xin Liu, Xin Liu, Xin Liu, Qian Ran, Qian Ran, Qian Ran, Jinjun Liang, Jinjun Liang, Jinjun Liang, Shaobo Shi, Shaobo Shi, Shaobo Shi, Bo Yang, Bo Yang, Bo Yang   +35 more
doaj   +1 more source

Differentiation of left ventricular deformation using 2D speckle tracking based on left ventricular geometric pattern in a hypertensive population: a single-center study

Arterial Hypertension
BACKGROUND: Left ventricular (LV) adaptation to arterial hypertension can result in different geometric responses with different hemodynamic patterns.
Mefri Yanni, Nani Nani, Wulan Prisilla
doaj   +1 more source

A Case of Multiple Mitochondrial Dysfunctions Syndrome 1 and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Multiple mitochondrial dysfunctions syndrome 1 (MMDS1, MIM #605711) due to NFU1 gene defects is an ultra‐rare autosomal recessive inborn error of metabolism associated with reduced function of NFU1 iron–sulfur cluster (ISC) scaffold protein.
Charles R. DiFalco, Aaron Williams, Claudia Soler‐Alfonso, Emily Waskow, Elizabeth Mizerik, Fernando Scaglia, Chaya N. Murali   +6 more
wiley   +1 more source

Thyroid-stimulating hormone and adverse left ventricular remodeling following ST-segment elevation myocardial infarction

, 2018
Background: Adverse left ventricular remodeling is one of the major determinants of heart failure and mortality in patients surviving ST-segment elevation myocardial infarction (STEMI).
Sebastian Johannes Reinstadler, Christina Tiller, Lukas Mueller, Gert Klug, Hans-Josef Feistritzer, Johannes Mair, Martin Reindl, Benjamin Henninger, Bernhard Metzler, Agnes Mayr, Christoph Brenner   +10 more
core   +1 more source

Therapy for Myhre Syndrome: Goals, Misconceptions, and Current Agents

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre Syndrome (MYHRS, MIM #139210) is a rare, multisystem connective tissue disorder caused by recurrent heterozygous gain‐of‐function pathogenic variants in the SMAD4 gene, a key player in TGF‐β signaling and a regulator of extracellular matrix homeostasis.
Alessandro De Falco, Alfonso Manuel D'Alessio, Nicola Brunetti‐Pierri   +2 more
wiley   +1 more source

Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley   +1 more source

Molecular imaging of ventricular remodeling [PDF]

Journal of Nuclear Cardiology, 2009
Zandbergen, H. R., Schellings, M. W. M.
openaire   +2 more sources

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source