Results 11 to 20 of about 179,560 (211)

HDAC-dependent ventricular remodeling [PDF]

Trends in Cardiovascular Medicine, 2013
Heart failure, a syndrome culminating the pathogenesis of many forms of heart disease, is highly prevalent and projected to be increasingly so for years to come. Major efforts are directed at identifying the means of preventing, slowing, or possibly reversing the unremitting progression of pathological stress leading to myocardial injury and ultimately
Min, Xie, Joseph A, Hill
openaire   +2 more sources

Thioredoxin and ventricular remodeling [PDF]

Journal of Molecular and Cellular Cardiology, 2006
Increasing bodies of evidence indicate that reactive oxygen species (ROS) produced by mitochondria and other sources play an essential role in mediating ventricular remodeling after myocardial infarction and the development of heart failure. Antioxidants scavenge ROS, thereby maintaining the reduced environment of cells and inhibiting ventricular ...
Tetsuro, Ago, Junichi, Sadoshima
openaire   +2 more sources

Cardiovascular Remodeling Experienced by Real-World, Unsupervised, Young Novice Marathon Runners. [PDF]

, 2020
Aims: Marathon running is a popular ambition in modern societies inclusive of non-athletes. Previous studies have highlighted concerning transient myocardial dysfunction and biomarker release immediately after the race.
Aengevaeren, Albert, Alpérovitch, Andersen, Arbab-Zadeh, Arem, Armstrong, Ashor, Banfi, Bassler, Bassler, Basso, Beaudry, Behr, Bhuva, Bhuva, Bouchard, Brennan, Breuckmann, Cave, Chugh, Cicchetti, Cornelissen, Costello, Eldridge, Gaudreault, Green, Hamer, Harris, Heidbuchel, Hewing, Howden, Jones, Joyner, Kasikcioglu, Katch, Kim, Kinova, Kyu, La Gerche, Lahrouchi, Lang, Lara, Lear, Lee, Lee, Lewington, Liou, Lippi, Mansour, Maranon, Marijon, Marijon, Maron, McDiarmid, McGuire, Merghani, Milanović, Mittleman, Mont, Moore, Mousavi, Möhlenkamp, Naci, Neilan, Neilan, Nocon, Ogawa, Papadakis, Papadakis, Petersen, Predel, Rosmini, Scherr, Schnohr, Sharma, Shave, Shave, Sierra, Siscovick, Society, Tahir, Viana, Warburton, Weiner, Wen, Williams, Williams, Wilson, Wisløff, Witham, Zemva, Zilinski   +92 more
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A review of the molecular mechanisms underlying the development and progression of cardiac remodeling [PDF]

, 2017
Pathological molecular mechanisms involved in myocardial remodeling contribute to alter the existing structure of the heart, leading to cardiac dysfunction.
Angelini, Francesco, Bordin, Antonella, Carrizzo, Albino, Chimenti, Isotta, DE FALCO, Elena, Forte, Maurizio, Frati, Giacomo, Nocella, Cristina, Pagano, Francesca, Palmerio, Silvia, Schiavon, Sonia, Schirone, Leonardo, Sciarretta, Sebastiano, Valenti, Valentina, Vecchione, Carmine, Yee, Derek   +15 more
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Computational modeling of acute myocardial infarction [PDF]

, 2016
This is an Accepted Manuscript of an article published by Taylor & Francis Group in Computer Methods in Biomechanics and Biomedical Engineering on October, 2016, available online at: http://www.tandfonline.com/10.1080/10255842.2015.1105965Myocardial ...
Kuhl, E., Sáez Viñas, Pablo
core   +2 more sources

Cathepsin A Mediates Ventricular Remote Remodeling and Atrial Cardiomyopathy in Rats With Ventricular Ischemia/Reperfusion

JACC: Basic to Translational Science, 2019
Summary: After myocardial infarction, remote ventricular remodeling and atrial cardiomyopathy progress despite successful revascularization. In a rat model of ventricular ischemia/reperfusion, pharmacological inhibition of the protease activity of ...
Mathias Hohl, PhD, Katharina Erb, Lisa Lang, Sven Ruf, PhD, Thomas Hübschle, PhD, Stefan Dhein, MD, Wolfgang Linz, PhD, Adrian D. Elliott, PhD, Prashanthan Sanders, MBBS, PhD, Olesja Zamyatkin, Michael Böhm, MD, Ulrich Schotten, MD, PhD, Thorsten Sadowski, PhD, Dominik Linz, MD, PhD   +13 more
doaj   +1 more source

Soluble ST2 levels and left ventricular structure and function in patients with metabolic syndrome [PDF]

, 2016
Background: A biomarker that is of great interest in relation to adverse cardiovascular events is soluble ST2 (sST2), a member of the interleukin family.
Beunza, Maite, Cardelli, Patrizia, Celic, Vera, Di Somma, Salvatore, Escribano, Elena, Floridi, Federico, Lopez-Andres, Natalia, Magrini, Laura, Majstorovic, Anka, Marino, Rossella, Melero, Amaia, Pencic-Popovic, Biljana, Roy, Ignacio, Salerno, Gerardo, Sljivic, Aleksandra   +14 more
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Nanoparticles for Postinfarct Ventricular Remodeling [PDF]

Nanomedicine, 2018
In recent years, tremendous progress has been made in the treatment of acute myocardial infarction, but pathological ventricular remodeling often causes survivors to suffer from fatal heart failure. Currently, there is no effective therapy to attenuate ventricular remodeling.
Dong, C., Ma, A., Shang, Lijun
openaire   +3 more sources

Effects of vildagliptin on ventricular function in patients with type 2 diabetes mellitus and heart failure: a randomized placebo-controlled trial [PDF]

, 2017
Objectives: This study sought to examine the safety of the dipeptidyl peptidase-4 inhibitor, vildagliptin, in patients with heart failure and reduced ejection fraction.
Bolli, Geremia B., Kothny, Wolfgang, Kozlovski, Plamen, Krum, Henry, Lewsey, James D., Lukashevich, Valentina, McMurray, John J.V., Ponikowski, Piotr   +7 more
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Ventricular androgenic-anabolic steroid-related remodeling: an immunohistochemical study [PDF]

, 2017
Background: Several fatal cases of bodybuilders, following a myocardial infarction after long exposure to androgenicanabolic steroids (AAS), are reported. In recent years, evidence has emerged of cases of heart failure related to AAS consumption, with no
Cecchi, Rossana, Ciallella, Costantino, DI LUCA, Natale Mario, Kimura, Akihiko, Kondo, Toshikazu, Muciaccia, Barbara, Nosaka, Mizuho, Sestili, Cristina   +7 more
core   +1 more source