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2023
Abstract The term ventricular remodelling refers to alterations in size, shape, and function due to the response of the ventricle to sustained stress. Initially, the remodelling response to pathological stress helps in compensating the cardiac performance, but over time the response becomes maladaptive and leads to ventricular ...
Javier Díez +1 more
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Abstract The term ventricular remodelling refers to alterations in size, shape, and function due to the response of the ventricle to sustained stress. Initially, the remodelling response to pathological stress helps in compensating the cardiac performance, but over time the response becomes maladaptive and leads to ventricular ...
Javier Díez +1 more
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Screening for ventricular remodeling
Current Heart Failure Reports, 2006Current guidelines emphasize the importance of preventing heart failure (HF) by targeting people with preclinical forms of the disease. Accordingly, there is considerable interest in identifying left ventricular (LV) remodeling, the fundamental substrate for HF, in asymptomatic individuals in the community.
Douglas S, Lee +2 more
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Controversies in ventricular remodelling
The Lancet, 2006Ventricular remodelling describes structural changes in the left ventricle in response to chronic alterations in loading conditions, with three major patterns: concentric remodelling, when a pressure load leads to growth in cardiomyocyte thickness; eccentric hypertrophy, when a volume load produces myocyte lengthening; and myocardial infarction, an ...
Lionel H, Opie +3 more
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Ventricular remodeling and infarct expansion
The American Journal of Cardiology, 1993Infarct expansion, defined as an alteration in the ventricular topography due to thinning and lengthening of the infarcted segment, develops within the first few hours of the acute symptoms, mostly in patients with a large, transmural, anterior myocardial infarction.
ZARDINI P +4 more
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Critical Care Nursing Clinics of North America, 2003
Ventricular remodeling is an extremely complicated process that is not well understood. There seem to be multiple feedback loops that respond to mechanical events as well as to neurohormonal stimulation, cytokine release, and other, yet unidentified, agents.
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Ventricular remodeling is an extremely complicated process that is not well understood. There seem to be multiple feedback loops that respond to mechanical events as well as to neurohormonal stimulation, cytokine release, and other, yet unidentified, agents.
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Cardiology, 2008
Ventricular remodeling is a repair process. It can follow myocardial infarction, mechanical overload (for example, in hypertension or valvular heart disease), and also occurs in inflammation and dilated cardiomyopathy. Remodeling can be an (early) adaptive process followed by a maladaptive (late) phase and involves all cells that are present in the ...
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Ventricular remodeling is a repair process. It can follow myocardial infarction, mechanical overload (for example, in hypertension or valvular heart disease), and also occurs in inflammation and dilated cardiomyopathy. Remodeling can be an (early) adaptive process followed by a maladaptive (late) phase and involves all cells that are present in the ...
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Aldosterone and Left Ventricular Remodeling
Hormone and Metabolic Research, 2015AbstractExperimental and clinical evidence obtained in the last 2 decades clearly indicates that protracted exposure to inappropriately elevated aldosterone levels causes significant changes in left ventricular structure and function. Animal studies have demonstrated that aldosterone induces myocardial inflammatory changes and fibrosis in the presence ...
CATENA, Cristiana +4 more
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Prevention of ventricular remodeling
Journal of Laboratory and Clinical Medicine, 1998Abstract Despite the major advances in our understanding of the process of ventricular remodeling, many issues remain unresolved. Some relate to the ongoing question of which signals are important in initiating structural changes in the myocardium. Specifically, a better understanding of infarct zone healing may allow for reduced regional and global ...
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MicroRNAs in right ventricular remodelling
Cardiovascular Research, 2017Right ventricular (RV) remodelling is a lesser understood process of the chronic, progressive transformation of the RV structure leading to reduced functional capacity and subsequent failure. Besides conditions concerning whole hearts, some pathology selectively affects the RV, leading to a distinct RV-specific clinical phenotype.
Sandor, Batkai +2 more
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Ventricular remodelling: consequences and therapy
European Heart Journal, 1993The mammalian left ventricle can change its size and shape in response to a variety of stimuli including loss of tissue and external work. These changes in size and shape, defined as remodelling, are the sum total of a number of processes that involve the myocyte and the interstitial fibrous structures which provide the matrix in which the myocyte ...
H N, Sabbah, S, Goldstein
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