Results 251 to 260 of about 557,721 (292)

Myocyte renewal and ventricular remodelling

Nature, 2002
Remaining young at heart is a desirable but elusive goal. Unbeknown to us, however, myocyte regeneration may accomplish just that. Continuous cell renewal in the adult myocardium was thought to be impossible, but multipotent cardiac stem cells may be able to renew the myocardium and, under certain circumstances, can be coaxed to repair the broken heart
Piero, Anversa, Bernardo, Nadal-Ginard
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Ventricular remodeling in heart failure

Journal of Cardiac Failure, 2002
This review briefly highlights the major mechanisms of left ventricular (LV) remodeling following myocardial infarction in heart failure and presents novel strategies to limit infarct size and retard the progression of LV remodeling. This is important since interventions that have been shown to improve mortality in patients with heart failure such as ...
Mohamed A, Gaballa, Steven, Goldman
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Myocyte proliferation and ventricular remodeling

Journal of Cardiac Failure, 2002
Improvement in the methodological approach to the analysis of the myocardium has provided clear evidence of cardiac myocyte proliferation, questioning the general belief that the growth of the adult heart under physiological and pathological conditions can occur only by cellular hypertrophy.
Annarosa, Leri, Jan, Kajstura, Piero, Anversa   +2 more
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Remodeling of ventricular repolarization in experimental right ventricular hypertrophy

Journal of Electrocardiology, 2017
To understand electrophysiological mechanisms that underlie the progression of compensated right ventricular hypertrophy (RVH) to heart failure, the purpose of the study was to evaluate remodeling of ventricular repolarization in connection with hemodynamic abnormalities and vulnerability of the heart ventricles to arrhythmias in RVH rats with ...
S N, Kharin, V V, Krandycheva, A S, Tsvetkova, K V, Shumikhin   +3 more
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Role of apoptosis in ventricular remodeling

Current Heart Failure Reports, 2005
Cell loss is a common feature in the failing heart, and this contributes to the relentless progression seen in patients with heart failure. Apoptosis is one of the most common causes of cell loss in animals and humans with heart failure. There is increasing evidence that apoptosis, even while occurring in a low-grade manner, can mediate heart failure ...
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Ventricular remodeling: Hype or hope?

Nature Medicine, 1996
An unconventional operation for treating end-stage heart failure may prove beneficial for some patients waiting for heart transplants.
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Reverse ventricular remodeling: mechanical options

Current Opinion in Cardiology, 2006
The aim of this review is to update the cardiovascular clinician on the current status of surgical therapies aimed at achieving reverse ventricular remodeling.Relevant research focusing on mechanical options for reverse ventricular remodeling will be referenced and summarized.Heart failure is a tremendous burden on society in terms of both lives lost ...
Edwin C, McGee, A Marc, Gillinov, Patrick M, McCarthy   +2 more
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Surgical ventricular remodeling

Current Opinion in Cardiology, 2017
The surgical management of patients with ischemic cardiomyopathy, especially those with left ventricular ejection fractions less than 20% has historically been controversial. The original trials of surgical revascularization versus medical therapy intentionally excluded those patients with an ejection fraction less than 35%. The significant advances in
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Myocyte cell death and ventricular remodeling

Current Opinion in Nephrology and Hypertension, 1997
The recognition that cell death in the myocardium is not only necrotic in nature but is also mediated by activation of the suicide program of myocytes has raised several questions concerning the magnitude of this phenomenon, and whether these two distinct forms of cell death are disease-dependent or coexist in the pathologic heart.
P, Anversa, G, Olivetti, A, Leri, Y, Liu, J, Kajstura   +4 more
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[Left ventricular remodelling].

Cardiologia (Rome, Italy), 1991
An acute myocardial infarction, particularly one that is large and transmural, can produce expansion and alterations in the topography of both the infarcted and non-infarcted regions or the ventricle. This remodelling can importantly affect the function of the ventricle and the prognosis. Side-to-side slippage of myocytes in the myocardium occurring in
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