Results 41 to 50 of about 188,365 (337)

Pathological Ventricular Remodeling [PDF]

open access: yesCirculation, 2013
Despite declines in heart failure morbidity and mortality with current therapies, rehospitalization rates remain distressingly high, substantially affecting individuals, society, and the economy. As a result, the need for new therapeutic advances and novel medical devices is urgent.
Jana S, Burchfield   +2 more
openaire   +5 more sources

Emerging role of angiogenesis in adaptive and maladaptive right ventricular remodeling in pulmonary hypertension [PDF]

open access: yes, 2018
Right ventricular (RV) function is the primary prognostic factor for both morbidity and mortality in pulmonary hypertension (PH). RV hypertrophy is initially an adaptive physiological response to increased overload; however, with persistent and/or ...
Bonnet, Sébastien   +3 more
core   +1 more source

Effects of candesartan, an angiotensin II receptor type I blocker, on atrial remodeling in spontaneously hypertensive rats [PDF]

open access: yes, 2015
Hypertension-induced structural remodeling of the left atrium (LA) has been suggested to involve the renin–angiotensin system. This study investigated whether treatment with an angiotensin receptor blocker, candesartan, regresses atrial remodeling in ...
Choisy, Stéphanie C.   +5 more
core   +1 more source

Pro/Anti-Inflammatory Cytokine Imbalance in Postischemic Left Ventricular Remodeling

open access: yesMediators of Inflammation, 2010
Objectives. Cytokines play an important role in left ventricular remodeling consequent to myocardial ischemia. The aim of this study was to correlate cytokine production and lymphocyte apoptosis to post-ischemic left ventricular remodeling in patients ...
Pasqui Anna Laura   +6 more
doaj   +1 more source

Cardioprotective effects of exercise training: the importance of nitric oxide [PDF]

open access: yes, 2008
Left ventricular remodeling after myocardial infarction is a compensatory mechanism, which serves to restore left ventricular pump function to normal levels.
Waard, M.C. (Monique) de
core  

Role of cardiac resynchronization therapy in the development of new-onset atrial fibrillation: A single-center prospective study. [PDF]

open access: yes, 2012
Albeit several studies examined the association between cardiac resynchronization therapy (CRT) and atrial fibrillation (AF) in heart failure (HF), results are still unclear and quite conflicting.
Cristofaro d'   +3 more
core   +3 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Maternal Cardiovascular Impairment in Pregnancies Complicated by Severe Fetal Growth Restriction [PDF]

open access: yes, 2012
—Fetal growth restriction and preeclampsia are both conditions of placental etiology and associated to increased risk for the long-term development of cardiovascular disease in the mother. At presentation, preeclampsia is associated with maternal global
Liberati, M   +3 more
core   +1 more source

Right ventricular remodeling in restrictive ventricular septal defect [PDF]

open access: yesJournal of Molecular and Cellular Cardiology, 2010
Restrictive ventricular septal defect (rVSD) presents with little/no hemodynamic aberrations despite a patent septal defect. Clinically, these patients are observed with the hope that the defect will functionally close over time without the need for surgical repair and development of heart failure.
Gretel, Monreal   +8 more
openaire   +2 more sources

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

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