Results 41 to 50 of about 1,071,989 (385)

Dual Endothelin Receptor Blockade Abrogates Right Ventricular Remodeling and Biventricular Fibrosis in Isolated Elevated Right Ventricular Afterload. [PDF]

PLoS ONE, 2016
BACKGROUND:Pulmonary arterial hypertension is usually fatal due to right ventricular failure and is frequently associated with co-existing left ventricular dysfunction. Endothelin-1 is a powerful pro-fibrotic mediator and vasoconstrictor that is elevated
Eva Amalie Nielsen, Mei Sun, Osami Honjo, Vibeke E Hjortdal, Andrew N Redington, Mark K Friedberg   +5 more
doaj   +1 more source

Traditional Chinese Medicine Intervenes Ventricular Remodeling Following Acute Myocardial Infarction: Evidence From 40 Random Controlled Trials With 3,659 Subjects

Frontiers in Pharmacology, 2021
Objectives: We intend to conduct a meta-analysis on the systematic evaluation of traditional Chinese medicine (TCM) in the treatment of ventricular remodeling following acute myocardial infarction (AMI).
Xiao-Xiao Zhang, Bo Liang, Chang-Le Shao, Ning Gu   +3 more
doaj   +1 more source

Implantation of a poly-L-lactide GCSF-functionalized scaffold in a model of chronic myocardial infarction [PDF]

, 2017
A previously developed poly-l-lactide scaffold releasing granulocyte colony-stimulating factor (PLLA/GCSF) was tested in a rabbit chronic model of myocardial infarction (MI) as a ventricular patch.
Chello, Massimo, Crescenzi, Anna, De Marco, Federico, Gambardella, Ivancarmine, Nappi, Francesco, Nenna, Antonio, Rainer, Alberto, Sedati, Pietro, Spadaccio, Cristiano, Taffon, Chiara, Trombetta, Marcella   +10 more
core   +1 more source

Left ventricle reverse remodeling in chronic aortic regurgitation patients with dilated ventricle after aortic valve replacement

Journal of Cardiothoracic Surgery, 2022
Background Aortic valve replacement (AVR) for chronic aortic regurgitation (AR) with a severe dilated left ventricle and dysfunction leads to left ventricle remodeling.
Ming-Kui Zhang, Li-Na Li, Hui Xue, Xiu-Jie Tang, He Sun, Qing-Yu Wu   +5 more
doaj   +1 more source

Autonomic neuro-cardiac profile of electrical, structural and neuronal remodeling in myocardial infarction-induced heart failure

Journal of Molecular and Cellular Cardiology Plus, 2023
Aims: Heart failure is a clinical syndrome typified by abnormal autonomic tone, impaired ventricular function, and increased arrhythmic vulnerability.
Shui Hao Chin, Emily Allen, Kieran E. Brack, G. André Ng   +3 more
doaj   +1 more source

Prognostic Implications of Right Ventricular Remodeling and Function in Patients with Significant Secondary Tricuspid Regurgitation.

Circulation, 2019
BACKGROUND In patients with significant (moderate and severe) tricuspid regurgitation (TR), the decision to intervene is influenced by right ventricular (RV) size and function. RV remodeling in significant secondary TR has been underexplored.
M. Dietz, E. Prihadi, P. van der Bijl, L. Goedemans, B. Mertens, E. Gursoy, O. S. van Genderen, N. Ajmone Marsan, V. Delgado, Jeroen J. Bax   +9 more
semanticscholar   +1 more source

Emerging role of angiogenesis in adaptive and maladaptive right ventricular remodeling in pulmonary hypertension [PDF]

, 2018
Right ventricular (RV) function is the primary prognostic factor for both morbidity and mortality in pulmonary hypertension (PH). RV hypertrophy is initially an adaptive physiological response to increased overload; however, with persistent and/or ...
Bonnet, Sébastien, de Jesus Perez, Vinicio A., Frump, Andrea L., Lahm, Tim   +3 more
core   +1 more source

The microRNA in ventricular remodeling: the miR-30 family

Bioscience Reports, 2019
Ventricular remodeling (VR) is a complex pathological process of cardiomyocyte apoptosis, cardiac hypertrophy, and myocardial fibrosis, which is often caused by various cardiovascular diseases (CVDs) such as hypertension, acute myocardial infarction ...
Xiaonan Zhang, Shaoyang Dong, Q. Jia, Ao Zhang, Yanyang Li, Yaping Zhu, Shichao Lv, Junping Zhang   +7 more
semanticscholar   +1 more source

Correlation Between Endothelial Dysfunction and Left Ventricular Remodeling in Patients with Chronic Kidney Disease

Kidney & Blood Pressure Research, 2014
Background/Aims: To investigate the role of endothelial dysfunction on left ventricular remodeling in patients with chronic kidney disease and to evaluate the correlation between endothelial dysfunction and left ventricular remodeling.
Tao Peng, Zhao Hu, Ling Wu, Dengren Li, Xiangdong Yang   +4 more
doaj   +1 more source

Effects of candesartan, an angiotensin II receptor type I blocker, on atrial remodeling in spontaneously hypertensive rats [PDF]

, 2015
Hypertension-induced structural remodeling of the left atrium (LA) has been suggested to involve the renin–angiotensin system. This study investigated whether treatment with an angiotensin receptor blocker, candesartan, regresses atrial remodeling in ...
Choisy, Stéphanie C., Choisy, Stéphanie C., Hancox, Jules C., James, Andrew F., Jones, Sandra A., Kim, Shang-Jin   +5 more
core   +1 more source