Results 131 to 140 of about 29,656 (290)

Caveolin-3 and Caveolae regulate ventricular repolarization. [PDF]

J Mol Cell Cardiol, 2023
Markandeya YS, Gregorich ZR, Feng L, Ramchandran V, O' Hara T, Vaidyanathan R, Mansfield C, Keefe AM, Beglinger CJ, Best JM, Kalscheur MM, Lea MR, Hacker TA, Gorelik J, Trayanova NA, Eckhardt LL, Makielski JC, Balijepalli RC, Kamp TJ.   +18 more
europepmc   +1 more source

Analysis of Ventricular Repolarization Parameters

, 2019
This bachelor’s thesis deals with the analysis of ventricular repolarization parameters on experimental ECG records. In the beginning of the theoretical part there are included information about heart electrophysiology, fundamental principle of ECG and ...
Abbrent, Jakub
core  

Small‐conductance Ca2⁺‐activated K⁺ channels in cardiac excitation–contraction coupling: Bridging mitochondria, sarcolemma and antiarrhythmic therapy

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondrial SK channel enhancement reduces cardiac arrhythmia trigger. Spontaneous sarcoplasmic reticulum (SR) Ca2+ release via hyperactive RyR2s underlies an increased arrhythmia trigger, promoting early and delayed afterdepolarizations during stress. Hyperactive RyR2s causes rise in cytosolic [Ca2+] during diastole. Clearance
Dmitry Terentyev, Alexey V. Glukhov, Vladimir Bogdanov, Aleksei S. Averin, Roland Veress, Bum‐Rak Choi, Shanna Hamilton, Andriy E. Belevych   +7 more
wiley   +1 more source

Determinants of electrocardiographic and spatial vectorcardiographic descriptors of ventricular repolarization in normal subjects

, 2001
he link between the dispersion of ventricular recovery times and arrhythmias has previously been demonstrated.(1) QT dispersion has been used to quantify the dispersion of ventricular refractoriness from the standard 12-lead electrocardiogram.(2) However,
Gialafos, E., Pantazis, A., Triposkiadis, F., Gialafos, J., Dilaveris, P.   +4 more
core   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Interaction of activation-repolarization coupling and restitution properties in two models of human ventricular tissue [PDF]

, 2013
Dispersion of repolarization time (or recovery time) is known to be pro-arrhythmic, but not much is known about the rate-dependency of dispersion in repolarization time.
Bozorgizadeh, Mahshid
core  

Evaluating the effect of Roxadustat on ventricular repolarization in patients undergoing peritoneal dialysis. [PDF]

Eur J Med Res, 2023
Zhang Y, Zhang L, Ge P, Xu R, Ye Z.
europepmc   +1 more source

Electrodiffusion in cardiac intercalated disc nanostructures alters cell–cell action potential transmission via ephaptic coupling: A model study

The Journal of Physiology, EarlyView.
Abstract figure legend Ephaptic phenomena in a high‐resolution model of the cardiac intercalated disc. Meshed representation of a tortuous intercalated disc that was generated based on electron and super‐resolution microscopy data. Na+ channels (red) and gap junctions (green) are heterogeneously distributed, with additional regions of reduced ion ...
Ena Ivanovic, Marina Vannucci, Nicolae Moise, Seth H. Weinberg, Jan P. Kucera   +4 more
wiley   +1 more source

Increased GIRK channel activity prevents arrhythmia in mice with heart failure by enhancing ventricular repolarization. [PDF]

Sci Rep, 2023
An X, Cho H.
europepmc   +1 more source

Intercalated disk structure, tissue heterogeneity and ion channel distribution modulate conduction and local calcium influx

The Journal of Physiology, EarlyView.
Abstract figure legend A, three‐dimensional representation of cardiac intercalated disk, reduced to a 100‐partition, computationally efficient network representation. B, ion dynamics within intercalated disk extracellular cleft space. C, rapid pacing leads to localized conduction block in tissue with regions of perturbed intercalated disk (ID ...
Nicolae Moise, Heather L. Struckman, James W. Smyth, Gregory S. Hoeker, Steven Poelzing, Rengasayee Veeraraghavan, Seth H. Weinberg   +6 more
wiley   +1 more source