Results 131 to 140 of about 192,432 (282)
Interactive Verifiable Secret Sharing Scheme
Commitment schemes, secret sharing schemes, interactive zero-knowledge proofs which underlie the offered interactive secrete sharing schemes are considered. Such schemes are one of the main computing primitives in the theory of secure computations.
O. V. Kazarin
doaj
From bricks to bytes: Verifiable data for decarbonizing the building sector
Amidst the pressing need to combat climate change and curb greenhouse gas (GHG) emissions, the building sector emerges as a pivotal sector, substantially impacting worldwide emissions.
Marc-Fabian Körner +3 more
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Key public verifiable MA-CP-ABE scheme based on aggregatable PVSS and consortium blockchain
To address challenges associated with threshold-based multi-authority ciphertext-policy attribute-based encryption (MA-CP-ABE), such as untrusted attribute authorities (AA) and the inability to verify the correctness of attribute private keys publicly, a
JING Xu, JIANG Yan
doaj +2 more sources
Interactive Verifiable Secret Sharing Scheme
Commitment schemes, secret sharing schemes, interactive zero-knowledge proofs which underlie the offered interactive secrete sharing schemes are considered.
O.V. Kazarin
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
SCI-Verifier: Scientific Verifier with Thinking
As large language models (LLMs) are increasingly applied to scientific reasoning, the complexity of answer formats and the diversity of equivalent expressions make answer verification a critical yet challenging task. Existing verification studies in scientific domains suffer from two major limitations: (a) the absence of systematic evaluation standards
Zheng, Shenghe +10 more
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source

