Results 141 to 150 of about 54,744 (297)
VeriFU: verifiable federated unlearning
Federated unlearning enables clients to withdraw their contributions from a global model.However, enabling clients to verify whether the server has honestly and effectively removed their contributions remains a critical challenge. To address this aspect,
Jiang Zehao +4 more
doaj
On the equivalence between classically verifiable position verification and certified randomness
Gate-based quantum computers can accelerate computational tasks beyond classical capabilities. Random circuit sampling is a task that has experimentally demonstrated algorithmic quantum advantage on near-term devices, but its practical utility has been ...
Fatih Kaleoglu +6 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Committing Encryption and Publicly-Verifiable SignCryption [PDF]
Encryption is often conceived as a committing process, in the sense that the ciphertext may serve as a commitment to the plaintext. But this does not follow from the standard definitions of secure encryption.
Yitchak Gertner, Amir Herzberg
core
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Hardness amplification of weakly verifiable puzzles [PDF]
Is it harder to solve many puzzles than it is to solve just one? This question has different answers, depending on how you define puzzles. For the case of inverting one-way functions it was shown by Yao that solving many independent instances ...
Ran Canetti +2 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source

