Results 121 to 130 of about 12,029,480 (253)

Detection of SARS-CoV-2 virus particles in Vero cells infected with passage 4 virus stocks.

open access: yes, 2021
A) After 4 passages of recovered wild type SARS-CoV-2 virus particles in Vero cells, naïve Vero cells were infected and fixed 72 h.p.i. Viral particles could be observed inside and outside of Vero cells indicated by red arrows. Scale bar, 2 μm. B) Higher
Adam Pickard (255057)   +6 more
core   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

open access: yesChemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier   +7 more
wiley   +1 more source

Interaction between submicron COD crystals and renal epithelial cells

open access: yesInternational Journal of Nanomedicine, 2012
Hua Peng1,2 Jian-Ming Ouyang1,2 Xiu-Qiong Yao1, Ru-E Yang11Department of Chemistry, Jinan University, 2Institute of Biomineralization and Lithiasis Research, Jinan University, Guangzhou, ChinaObjectives: This study aims to investigate the adhesion ...
Peng H, Ouyang JM, Yao XQ, Yang RE
doaj  

Purification and Characterization of Enterovirus 71 Viral Particles Produced from Vero Cells Grown in a Serum-Free Microcarrier Bioreactor System

open access: yesPLoS ONE, 2011
Background Enterovirus 71 (EV71) infections manifest most commonly as a childhood exanthema known as hand-foot-and-mouth disease (HFMD) and can cause neurological disease during acute infection. Principal Finding In this study, we describe the production,
Chia-Chyi Liu   +9 more
semanticscholar   +1 more source

Substrate‐Selective Inhibition of the SARS‐CoV‐2 Papain‐Like Protease: Inhibition of Hydrolysis of Human Over Viral Substrates

open access: yesChemistry – A European Journal, EarlyView.
The SARS‐CoV‐2 papain‐like protease (PLpro) is a medicinal chemistry target. Here we report mass spectrometry assays employing oligopeptide substrates based on the sequences of the viral polyproteins 1a/1ab and on an ISG15‐modified human protein, which enabled the identification of substrate‐selective PLpro inhibitors.
Sakshi Sharma   +13 more
wiley   +1 more source

Cellular tropism and cell-to-cell fusion properties of the infectious bronchitis virus spike glycoprotein [PDF]

open access: yes
There are numerous vaccines available for the control of infectious bronchitis virus (IBV) in poultry, however protection is short-lived and poorly cross-protective between strains.
Bickerton, Erica Jane
core  

Generation of Vero E6 cells stably expressing PEDV N.

open access: yes, 2019
Vero E6-N cells were generated by lentivirus transduction. Growth kinetics of Vero E6 and Vero E6-N cells were compared (A). PEDV N expression was analyzed by Western blotting of cell lysate (B) and immunofluorescence (C) with anti-PEDV N antibody ...
Peera Jaru-Ampornpan (6429272)   +4 more
core   +1 more source

Pathway of rubella virus infectious entry into Vero cells

open access: yesJournal of General Virology, 1996
The mechanism and the kinetics of rubella virus (RV) penetration into Vero cells were studied. By using pronase or acid treatment to inactivate virus which had adsorbed to cell membrane but had not been internalized, it was found that a period of 7 h was required in order for all of the adsorbed virus to enter the host cells.
PETRUZZIELLO R   +5 more
openaire   +2 more sources

Mass culture of equine synovial fluid‐derived mesenchymal stromal cells using nonwoven polyethylene terephthalate fabrics

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Culture protocols need to yield 100 million equine synovial fluid (SF)‐derived mesenchymal stromal cells (SF‐MSCs) in around 3 weeks are needed, before these cells can be evaluated as agents of articular repair in clinical trials. Objectives To investigate mass culture of equine SF‐MSC culture protocols using nonwoven polyethylene ...
Miho Daniel Yoshitomi   +5 more
wiley   +1 more source

Toxicity studies of natural product in vero cells using impedance monitoring

open access: yes, 2017
Natural products have traditionally been used for medicinal purposes in Asian communities. Toxicity studies typically use animal testing to predict the harmfulness of a particular substance to human health.
Mansor, Ahmad Fairuzabadi   +4 more
core  

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