Results 101 to 110 of about 72,292 (222)

Native Label‐Free Spectral Biochemical Fingerprinting of an Enveloped Mammalian RNA Virus Reveals Mode of Action of a Virucidal Drug

open access: yesSmall Methods, EarlyView.
Deep‐Ultraviolet Resonance Raman (DUVRR) spectroscopy is introduced as a label‐free, non‐invasive analytical workflow for the biochemical fingerprinting of enveloped viruses. By integrating bottom‐up stoichiometric reconstruction with top‐down biochemical extraction, this strategy accurately disentangles complex viral compositions in physiological‐like
Denis Rajnovic   +8 more
wiley   +1 more source

Genome Analysis of Corynebacterium ulcerans Isolates Chronologically Recovered From the Same Cat for Two Years: Circulation in a Cat Shelter

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT Toxigenic Corynebacterium ulcerans, a zoonotic pathogen, was isolated repeatedly from a cat in an in‐house group in Japan. Although the cat was cured once by antibiotic treatment, clonal isolates of the original pathogenic strain were recovered repeatedly during a 2‐year course.
Ryoko Jikihara   +8 more
wiley   +1 more source

Construction of a Vero cell line expression human KREMEN1 for the development of CVA6 vaccines

open access: yesVirology Journal
Coxsackievirus A6 (CVA6) has emerged as a major pathogen causing hand, foot and mouth disease (HFMD) outbreaks worldwide. The CVA6 epidemic poses a new challenge in HFMD control since there is currently no vaccine available against CVA6 infections.
Dongqing Zhang   +13 more
doaj   +1 more source

Drivers of Host–Pathogen Community Assemblages in European Forests and Urban Green Spaces

open access: yesIntegrative Zoology, EarlyView.
ABSTRACT Despite advances in understanding infectious diseases, the persistence and re‐emergence of wildlife pathogens continue to raise public and veterinary health concerns. This study investigates the relationship between biodiversity and rodent‐borne diseases in Europe, focusing on habitat alterations and their impact on rodent diversity.
Vincent Sluydts   +21 more
wiley   +1 more source

Influence of degree of conversion on the cytotoxicity of 3D‐printed denture base resins. A scoping review

open access: yesJournal of Prosthodontics, EarlyView.
Abstract Purpose Evidence regarding the cytotoxicity of 3D‐printed denture base resins and the role of degree of conversion remains limited and heterogeneous. Therefore, this scoping review aimed to map existing in vitro evidence and explore how degree of conversion and post‐processing factors are reported in relation to biological outcomes.
Nathan Felipini Ferreira   +5 more
wiley   +1 more source

SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu   +5 more
wiley   +1 more source

Mass culture of equine synovial fluid‐derived mesenchymal stromal cells using nonwoven polyethylene terephthalate fabrics

open access: yesEquine Veterinary Journal, Volume 58, Issue 5, Page 1454-1466, September 2026.
Abstract Background Culture protocols need to yield 100 million equine synovial fluid (SF)‐derived mesenchymal stromal cells (SF‐MSCs) in around 3 weeks are needed, before these cells can be evaluated as agents of articular repair in clinical trials. Objectives To investigate mass culture of equine SF‐MSC culture protocols using nonwoven polyethylene ...
Miho Daniel Yoshitomi   +5 more
wiley   +1 more source

Mpox Airborne Transmission: A Systematic Review

open access: yesReviews in Medical Virology, Volume 36, Issue 5, September 2026.
ABSTRACT Since May 2022, mpox has been reported across multiple nonendemic regions, with concurrent outbreaks in diverse geographic settings, raising concerns about broader international spread. However, evidence regarding the risk of airborne transmission remains limited.
Lucas Ferreira Theotonio dos Santos   +6 more
wiley   +1 more source

Molecular and Serological Screening of West Nile and Usutu Virus in Birds and Humans: A Sentinel Study in Finland

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
We developed sensitive real‐time PCR assays for West Nile virus and Usutu virus to screen bird and human samples in Finland. Although no positive samples were detected, active migratory flyways and recent cases in neighbouring countries highlight the risk of future introduction and the need for continued surveillance.
Ruut Joensuu   +6 more
wiley   +1 more source

Ligand‑Based Virtual Screening Discovery of Thienopyrimidinone Derivatives as Allosteric nSMase2 Modulators and Antivirals Against West Nile Virus

open access: yesChemMedChem, Volume 21, Issue 16, 27 August 2026.
Ligand‐based virtual screening of over five million compounds identifies a thienopyrimidinone hit as a novel allosteric nSMase2 modulator. Structure‐guided optimisation improves inhibitory potency and delivers derivatives with antiviral activity against West Nile virus, expanding the chemical space of nSMase2 inhibitors and supporting host‐directed ...
Hadrián Álvarez‐Fernández   +6 more
wiley   +1 more source

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