Results 141 to 150 of about 3,238 (232)

ChemGraphX: an open-source web tool for computing topological indices and entropy measures. [PDF]

J Cheminform
Jacob K, Clement J, Arockiaraj M, Jindal A.   +3 more
europepmc   +1 more source

An Integrated DNA Nanoprobe for Intranuclear Imaging and in Situ Profiling of OGG1 Activity

Advanced Science, EarlyView.
The TP‐SA nanoprobe, integrating an AS1411 aptamer for nuclear delivery and a FRET array for signal amplification, enables real‐time tracking of nuclear OGG1 activity. It reveals cell‐line‐specific basal OGG1 levels and shows clinical promise using pneumonia patients’ lavage fluid.
Mingzhu Zhao, Xuemei Sun, He Li, Bangming Wang, Mengting Pan, Zhen Ma, Rong‐Mei Kong, Weiheng Kong, Yan Zhao, Fengli Qu   +9 more
wiley   +1 more source

Matrix metalloproteinases and disease severity among PI*MZ and PI*ZZ individuals in the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis (GRADS) cohort. [PDF]

BMJ Open Respir Res
Tejwani V, Bowler RP, Serban KA, Pratte KA, Ortega VE, Stoller JK, Kaminski N, Strange C.   +7 more
europepmc   +1 more source

An Edible Biohybrid Platform Accomplishes In Situ Fenton‐Mediated Enteral Nanoplastics Aging and Excretion

Advanced Science, EarlyView.
An edible biohybrid platform triggers nanoplastics (NPs) aging and agglomeration by in situ generating hydroxyl radicals within the intestine. The enlarged NPs are unable to penetrate the intestine and are subsequently excreted. Simultaneously, probiotic biofilms reinforce the intestinal barrier.
Su Zhou, Anran Yan, Haowei Guo, Ping Chen, Qiang Chu   +4 more
wiley   +1 more source

On Energy of Graphs with Self-Loops

Let G be a simple graph on n vertices with vertex set V(G). The energy of G, denoted by, $\mathcal{E}(G)$ is the sum of all absolute values of the eigenvalues of the adjacency matrix $A(G)$.
Das, Kinkar Chandra, Rakshith, B. R., Manjunatha, B. J.   +2 more
core   +1 more source

When Alzheimer's pathology meets cardiometabolic risk: intrinsic subcortical-cortical connectivity signatures of retroactive interference in aging. [PDF]

Alzheimers Res Ther
Altahona-Medina MA, Fernandez-Alvarez M, Lopez-Vilaret KM, Rugg MD, Cantero JL, Atienza M.   +5 more
europepmc   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

Advanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg, Irina Wachter, Agnieszka Pancholi, Matthias Akyel, Yomna Gohar, Priya Kumar, Ana Miguel Fernandes, Yuzhi Bao, Alica Schmidt‐Heydt, Marcel Piepers, Alicia Günthel, Marcel Sobucki, Elisa Kämmer, Süheyla Eroğlu‐Kayıkçı, Stephan Allgeier, Sylvia Erhardt, Vasily Zaburdaev, Carmelo Ferrai, Lennart Hilbert   +18 more
wiley   +1 more source

Lung disease in never-smokers with severe α₁-antitrypsin deficiency: the EARCO Registry. [PDF]

ERJ Open Res
Premuda C, Aljama C, Granados G, Ferrarotti I, Corsico AG, Turner AM, Torres-Duran M, Tanash H, Rodríguez-García C, Jensen JS, Mantero M, Blasi F, Miravitlles M, Barrecheguren M, Esquinas C.   +14 more
europepmc   +1 more source

Construction of Sabatier Volcanoes for CO2 Hydrogenation to C1‐2 Oxygenates Using Data‐Efficient Machine Learning

Advanced Science, EarlyView.
A new data‐efficient framework combining DFT calculations, a neural network model, and automated graph analysis of catalytic reaction networks is proposed and applied to CO2 hydrogenation on transition metal nanoparticles. The analysis shows how efficient C2 oxygenate production requires a balance between CHx formation, C–C coupling, protonation, and ...
Mikhail V. Polynski, Sergey M. Kozlov
wiley   +1 more source

An adaptive slicing algorithm based on model contour information. [PDF]

PLoS One
Han X, Liu X, Lu K, Cui L.
europepmc   +1 more source