Results 51 to 60 of about 2,215,344 (291)

The impact of the variation in vertical load and the presence of openings on the mechanical response of masonry walls [PDF]

E3S Web of Conferences
This article aims to analyse the mechanical response of masonry walls under cyclic loading using the finite element method with Abaqus software. The proposed model has been validated using available numerical and experimental results.
Khanfri Chaimae, Mouhat Ouadia, Elrhaffari Younes, El Mennaouy Fatima, Rougui Mohamed   +4 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Energy-Saving Impact and Optimized Control Scheme of Vertical Load on Distributed Electric Wheel Loader

World Electric Vehicle Journal
During the operation of a wheel loader, the external load acting on the bucket undergoes many changes, resulting in significant changes in the load ratio on the front and rear axles. For this reason, controlling a standard wheel loader is not trivial. In
Wenlong Shen, Yunwu Han, Xiaotao Fei, Changying Ji   +3 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Effect of variable resistance training on lower limb strength and power development: A training study [PDF]

, 2010
The ability to develop high levels of muscular strength and power is considered to be a critical component in many, if not most, sports. Because of this, new training methods are constantly being sought in an attempt to improve strength and power ...
Dobbs, Caleb W.
core   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Interlayer Mechanical Behavior in CRTS II Slab Ballastless Tracks Under Vertical Loading

Applied Sciences
Reliable in situ quantification of interlayer mechanics in CRTS-II ballastless track slabs remains limited by the poor instrumentability of the CA mortar layer. This study implements a quasi-distributed fiber-optic sensing scheme by encapsulating FBGs in
Xiao Guo, Xiaonan Xie, Xuebing Zhang, Li Wang, Ping Xiang   +4 more
doaj   +1 more source

Analytical method for stress of granular medium foundation under vertical load

Yantu gongcheng xuebao, 2017
The analytical method for stress of foundation under vertical load is an important basis of design and computation in foundation engineering. However, the existing methods cannot reflect the properties of granular media for foundation soils.
CAO Wen-gui 1, HE Min 1, WANG Jiang-ying 2
doaj   +1 more source

The Influence of Control Law on Yaw Maneuver Load about Civil Aircraft

Hangkong gongcheng jinzhan, 2020
The fast and sharp deflection of rudder in aircraft maneuvering process can produce large aerodynamic loading on rudder and vertical fin, and transmit them to the rear fuselage, even cause the safety accident of reciprocated rudder pedalling of pilot ...
RUAN Wenbin, ZHANG Zhi
doaj   +1 more source