Results 21 to 30 of about 2,416,251 (240)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Weak Meson Vertices and the Hypernuclear Potential

open access: yesFizika B : a journal of experimental and theoretical physics, 2001
This paper is a continuation of an earlier paper on hypernuclear potentials. A novel derivation of the hypernuclear strangeness-violating potential due to the pseudoscalar meson exchanges is presented. Comparison with the earlier method shows that the theoretical uncertainty is less than 30%.
Barbero, Cesar   +4 more
openaire   +4 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Flexural–torsional behavior of thin-walled composite box beams using shear-deformable beam theory [PDF]

open access: yes, 2008
This paper presents a flexural–torsional analysis of thin-walled composite box beams. A general analytical model applicable to thin-walled composite box beams subjected to vertical and torsional loads is developed.
Chandra   +15 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

A Computational Study of Vertical Partial Gate Carbon Nanotube FETs

open access: yes, 2007
A vertical partial gate carbon nanotube (CNT) field-effect transistor (FET), which is amenable to the vertical CNT growth process and offers the potential for a parallel CNT array channel, is simulated using a self-consistent atomistic approach.
Fodor, James, Guo, Jing, Yoon, Youngki
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Interplay of transitions between oscillations with emergence of fireballs and quantification of phase coherence, scaling index in a magnetized glow discharge plasma of toroidal assembly

open access: yes, 2017
Interplay of transition of floating potential fluctuations in a glow discharge plasma in the toroidal vacuum vessel of SINP tokamak has been observed.
Ghosh, Sabuj   +4 more
core   +1 more source

Vertical wind profile characterization and identification of patterns based on a shape clustering algorithm [PDF]

open access: yes, 2019
Wind power plants are becoming a generally accepted resource in the generation mix of many utilities. At the same time, the size and the power rating of individual wind turbines have increased considerably.
Bueso Sánchez, María del Carmen   +4 more
core   +2 more sources

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