Results 91 to 100 of about 720,850 (319)

Proton Synchrotron Origin of the Very-high-energy Emission of GRB 190114C

open access: yesThe Astrophysical Journal, 2023
We consider here a proton-synchrotron model to explain the MAGIC observation of GRB 190114C afterglow in the energy band of 0.2–1 TeV, while the X-ray spectra are explained by electron-synchrotron emission.
Hebzibha Isravel   +2 more
doaj   +1 more source

Low-Energy Electron Inelastic Mean Free Path of Graphene Measured by a Time-of-Flight Spectrometer

open access: yesNanomaterials, 2021
The detailed examination of electron scattering in solids is of crucial importance for the theory of solid-state physics, as well as for the development and diagnostics of novel materials, particularly those for micro- and nanoelectronics.
Ivo Konvalina   +10 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

XMM-Newton observations of HESS J1813-178 reveal a composite Supernova remnant [PDF]

open access: yes, 2007
We present X-ray and 12CO(J=1-0) observations of the very-high-energy (VHE) γ-ray source HESS J1813-178 with the aim of understanding the origin of the γ-ray emission.
Funk, S.   +3 more
core  

Diffuse galactic sub-MeV γ-ray excess from high-energy electrons [PDF]

open access: yes, 2005
Recent INTEGRAL observations have confirmed the existence of diffuse sub-MeV radiation from the inner Galaxy. We propose a new explanation for the origin of this diffuse component in terms of electrostatic bremsstrahlung radiation from high-energy ...
R. Schröder   +6 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A proposed very high energy electron-proton collider, VHEeP

open access: yes, 2016
The possibility of using plasma wakefield acceleration to build a very high energy electron-proton (VHEeP) collider at a centre-of-mass energy of 9 TeV was presented at the DIS2015 workshop. In this talk, the physics case was further developed and the idea has since been published as a journal paper.
Wing, M., Caldwell, A.
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Substorm related changes in precipitation in the dayside auroral zone-a multi instrument case study [PDF]

open access: yes, 2002
International audienceA period (08:10?14:40 MLT, 11 February 1997) of enhanced electron density in the D- and E-regions is investigated using EISCAT, IRIS and other complementary instruments.
J. Manninen (7637285)   +20 more
core   +1 more source

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