Results 111 to 120 of about 10,153 (225)

Daily intermittent fasting is an effective multiscale treatment in preclinical models of absence epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Absence epilepsy is characterized by brief but frequent seizures with loss of consciousness. Existing treatments, which come with heavy side effects, are only partially effective and do not address the associated comorbidities, including cognitive and social deficits.
Coline Rulhe   +9 more
wiley   +1 more source

Impacts of Lifestyle and Microbiota‐Targeted Interventions for Overweight and Obesity on the Human Gut Microbiome: A Systematic Review

open access: yesObesity Reviews, EarlyView.
Dietary interventions showed the strongest evidence for improving microbiome composition. Probiotics and prebiotics consistently increased beneficial bacteria. Exercise and fecal microbiota transplantation had limited evidence but showed potential for microbiome modulation.
Yee Teng Lee   +6 more
wiley   +1 more source

Effect of very low-calorie ketogenic diet in combination with omega-3 on inflammation, satiety hormones, body composition, and metabolic markers. A pilot study in class I obese subjects [PDF]

open access: hybrid, 2021
Mariangela Rondanelli   +8 more
openalex   +1 more source

Nutrition Strategies for Next‐Generation Incretin Therapies: A Systematic Scoping Review of the Current Evidence

open access: yesObesity Reviews, EarlyView.
ABSTRACT Next‐generation incretin therapies, including semaglutide and tirzepatide, have transformed obesity and Type 2 diabetes management. However, evidence‐based nutritional strategies to support safe and effective use of these agents remain limited.
Marie Spreckley   +2 more
wiley   +1 more source

The Complex Relation of Branched‐Chain Amino Acids and Inflammation in the Obesity and Diabetes Context

open access: yesObesity Reviews, EarlyView.
ABSTRACT In a scenario with increasing cases of obesity and diabetes worldwide, branched‐chain amino acids (BCAA) metabolism has become an important factor in the understanding of these pathologies. More recently, its chronic high plasma levels have been postulated, alongside glucose, inflammatory factors, and other molecules, as an important ...
Bernardo Starling‐Soares   +4 more
wiley   +1 more source

An Evolutionary and Mechanistic Perspective on Dietary Carbohydrate Restriction in Cancer Prevention [PDF]

open access: yes, 2013
The confluence of basic cell biochemistry, epidemiological and anthropologic evidence points to high dietary carbohydrate and the associated disruption of the glucose-insulin axis as causes of the current increase in metabolic disorders, metabolic ...
Fine, Eugene J.
core  

Starvation of Cancer via Induced Ketogenesis and Severe Hypoglycemia

open access: yes, 2014
Neoplasms are highly dependent on glucose as their substrate for energy production and are generally not able to catabolize other fuel sources such as ketones and fatty acids.
Kapelner, Adam, Vorsanger, Matthew
core   +1 more source

Proceedings of the 1st annual symposium of the German Society for Paleo Nutrition held in 2013 [PDF]

open access: yes, 2013
Evolutionary Medicine is an emerging medical field that mainly addresses the causes of diseases under the consideration of evolutionary principles [1].
Klement, Rainer J.
core   +1 more source

Acute ketone monoester ingestion lowers resting cerebral blood flow: a randomized cross‐over trial

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This double‐blind, placebo‐controlled, randomized cross‐over trial investigated the effects of ketone monoester (KME) ingestion on resting cerebral blood flow (CBF) in young adults. We demonstrate that KME supplementation lowers CBF in a dose‐dependent manner over 2‐houra post‐ingestion, whereas CBF remained unchanged following ...
Aedan J. Rourke   +7 more
wiley   +1 more source

Effects of ketogenic diets on polycystic ovary syndrome: a systematic review and meta-analysis

open access: yesReproductive Biology and Endocrinology
Background This systematic review and meta-analysis aimed to evaluate the effects of ketogenic diet (KD) and very-low-energy ketogenic therapy (VLEKT) protocols on various health outcomes in patients with polycystic ovary syndrome (PCOS) and increased ...
Rossella Cannarella   +7 more
doaj   +1 more source

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