Results 151 to 160 of about 380,048 (349)

In vitro uptake and hydrolysis, by rat tissues, of cholesterol esters of a very low density, chyle lipoprotein fraction

, 1964
Nathan Brot, W.J. Lossow, I.L. Chaikoff
openalex   +1 more source

Metabolism of cholesteryl esters of rat very low density lipoproteins. [PDF]

, 1975
Ole Færgeman, Richard J. Havel
openalex   +1 more source

Structural Basis for the Interaction of Fibrin with the Very Low-Density Lipoprotein Receptor Revealed by NMR and Site-Directed Mutagenesis. [PDF]

Biochemistry, 2021
Gruschus JM, Yakovlev S, Banerjee K, Medved L, Tjandra N.   +4 more
europepmc   +1 more source

The GRK2/AP‐1 Signaling Axis Mediates Vascular Endothelial Dysfunction and Atherosclerosis Induced by Oscillatory Low Shear Stress

Advanced Science, EarlyView.
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu, Yi Shi, Chao‐Hua Kong, Ai‐Qun Chen, Ying Kang, Jun‐Yan Kan, Xiao‐Min Jiang, Peng Chu, Dong‐Chen Wang, Yi‐Fei Lv, Zhi‐Yuan Qian, Zi‐Hao Jiang, Yun‐Wei Chen, Yue Sun, Rui‐Rui Chang, Wen‐Ying Zhou, Yue Gu, Jun‐Xia Zhang, Shao‐Liang Chen   +18 more
wiley   +1 more source

Fatty acids differentially regulate hepatic cholesteryl ester formation and incorporation into lipoproteins in the liver of the mouse

Journal of Lipid Research, 2002
These experiments tested the hypothesis that fatty acids (FAs) that drive cholesterol esterification also enhance sterol secretion and were undertaken using a mouse model where lipoprotein-cholesterol output by the liver could be assessed in vivo.
Chonglun Xie, Laura A. Woollett, Stephen D. Turley, John M. Dietschy   +3 more
doaj  

ATF3 Deficiency Exacerbates Ageing‐Induced Atherosclerosis and Clinical Intervention Strategy

Advanced Science, EarlyView.
Targeting ATF3 with terazosin to against VSMC Senescence and atherosclerosis. TZ reduces the binding affinity of YTHDF2 to Atf3 mRNA, while enhancing mRNA stability. ATF3 promotes Atg7 transcription, enhancing autophagy. ATG7 binds to ATF3 in the cytoplasm, facilitating ATF3 translocation to the nucleus and establishing positive feedback. By modulating
Hao Nie, Tianyi Ji, Zixin Wan, Jie Huang, Han Li, Lingjiao Zou, Zhen Yang, Jiarui Li, Yuqi Guan, Lei Ruan, Jinhua Yan, Cuntai Zhang   +11 more
wiley   +1 more source

Effect of apoC-III gene polymorphisms on the lipoprotein-lipid profile of viscerally obese men

Journal of Lipid Research, 2003
Abdominal visceral adipose tissue (AT) accumulation is associated with an atherogenic metabolic profile that includes increased plasma triglyceride (TG), low HDL cholesterol levels, and an insulin-resistant hyperinsulinemic state.
Charles Couillard, Marie-Claude Vohl, James C. Engert, Isabelle Lemieux, Alain Houde, Natalie Alméras, Denis Prud’homme, André Nadeau, Jean-Pierre Després, Jean Bergeron   +9 more
doaj  

CD74 Blockade Disrupts Endothelial Migrasome Signaling to Prevent Inflammatory Macrophage Differentiation and Inhibit Atherosclerotic Progression

Advanced Science, EarlyView.
Migrasomes play a crucial role in endothelial‐immune interactions in atherosclerosis. This study identifies migrasomes as amplifiers in the inflammatory cascade, driving immune‐metabolic reprogramming via “migrasome‐APP‐CD74” signaling. Blocking CD74 disrupts migrasome‐mediated signaling, attenuating atherosclerosis progression.
Kangnan Zhang, Jiong Chen, Zhenhua Zhu, Hong Hu, Qinghui Zhang, Rongrong Jia, Na Wang, Shihao Xiang, Yong Zhou, Yuehong Wang, Ling Xu   +10 more
wiley   +1 more source

Hyperlipidemia and atherosclerosis associated with liver disease in ferrochelatase-deficient mice1

Journal of Lipid Research, 2001
Erythropoietic protoporphyria (EPP) is an inherited disorder of heme synthesis caused by deficiency of the mitochondrial enzyme ferrochelatase. EPP in humans is associated with liver disease, hypertriglyceridemia, and a low level of high density ...
Vincent W. Bloks, Torsten Plösch, Harry van Goor, Han Roelofsen, Juul Baller, Rick Havinga, Henkjan J. Verkade, Aad van Tol, Peter L.M. Jansen, Folkert Kuipers   +9 more
doaj  

Decreased Efficiency of Very-Low-Density Lipoprotein Lipolysis Is Linked to Both Hypertriglyceridemia and Hypercholesterolemia, but It Can Be Counteracted by High-Density Lipoprotein. [PDF]

Nutrients, 2021
Wieczorek E, Ćwiklińska A, Kuchta A, Kortas-Stempak B, Gliwińska A, Jankowski M.   +5 more
europepmc   +1 more source