Results 201 to 210 of about 256,414 (241)

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu, Gui‐Qin Liu, Ya‐Ping Peng, Li‐Ling Zhang, Xian‐Jin Wang, Liang‐Chuan Chen, Yuan‐Xi Zheng, Xue‐Jun Xiang, Rui Qiao, Xian‐He Lin   +9 more
wiley   +1 more source

Assessing the link of malnutrition with diabetes and mortality risk in heart failure patients

ESC Heart Failure, EarlyView.
Abstract Aims Malnutrition is increasingly recognized as a significant factor influencing the clinical outcomes of patients with heart failure (HF). Diabetes exacerbates risks like hospitalizations and mortality due to cardiovascular complications. The aim of this study was to explore the association of malnutrition with diabetes and its prognostic ...
Konstantinos Prokopidis, Yang Chen, Yang Liu, Ziyi Zhong, Jordi Morwani‐Mangnani, Daniel J. Cuthbertson, Rajiv Sankaranarayanan, Gregory Y.H. Lip, Masoud Isanejad   +8 more
wiley   +1 more source

Manipulation of very low density lipoprotein metabolism to reduce fat deposition in poultry [PDF]

Abdullah, Norhani, Foo, Hooi Ling, H., Ramlah, Idrus, Zulkifli, Loh, Teck Chwen, Tan, Bee Koon   +5 more
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A new model for very low density lipoprotein metabolism—Nomenclature for very low density lipoprotein derivatives

Journal of Theoretical Biology, 1980
Abstract A new model for the catabolism of very low density lipoprotein will be proposed following a brief discussion of the relevant information about its metabolism. This model is based on the assumption that each very low density lipoprotein derivative has a distinct structural feature which determines its biological fate.
Yunhua Jeng, Ingming Jeng
openaire   +3 more sources

Very-low-density lipoprotein assembly and secretion

Current Opinion in Lipidology, 2001
The assembly of apolipoprotein B (apoB) into VLDL is broadly divided into two steps. The first involves transfer of lipid by the microsomal triglyceride transfer protein (MTP) to apoB during translation. The second involves fusion of apoB-containing precursor particles with triglyceride droplets to form mature VLDL. ApoB and MTP are homologs of the egg
Gregory S. Shelness, Jeremy A. Sellers
openaire   +2 more sources

Very low density lipoprotein binding to adipocytes

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1980
Human very low density lipoprotein (VLDL) has been found to interact with both isolated adipocytes and adipocyte membranes in a manner which is saturable, reversible and dependent on time and temperature. Except for a difference in maximum binding capacity, a similar pattern is seen with both rat epididymal adipocytes and human omental adipocytes.
Kappu S. Desai, George Steiner, Charles H. Hollenberg, Ichiro Takeuchi   +3 more
openaire   +3 more sources

On the metabolic conversion of human plasma very low density lipoprotein to low density lipoprotein

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1973
Abstract The relationship of 125I-labelled apoproteins of very low density lipoprotein to that of other lipoproteins was studied in humans during steady-state conditions and following heparin injection. Heterogeneous metabolism of very low density lipo-protein apoproteins in normal individuals was apparent during steady-state conditions ...
Robert I. Levy, Frank T. Lindgren, Shlomo Eisenberg, David W. Bilheimer   +3 more
openaire   +3 more sources