Results 121 to 130 of about 529,645 (391)

Hydrodynamics and rheology of a vesicle doublet suspension [PDF]

open access: yesarXiv, 2019
The dynamics of an adhesive two-dimensional vesicle doublet under various flow conditions is investigated numerically using a high-order, adaptive-in-time boundary integral method. In a quiescent flow, two nearby vesicles move slowly towards each other under the adhesive potential, pushing out fluid between them to form a vesicle doublet at equilibrium.
arxiv  

High-volume fraction simulations of two-dimensional vesicle suspensions [PDF]

open access: yes, 2013
We consider numerical algorithms for the simulation of the rheology of two-dimensional vesicles suspended in a viscous Stokesian fluid. The vesicle evolution dynamics is governed by hydrodynamic and elastic forces. The elastic forces are due to local inextensibility of the vesicle membrane and resistance to bending.
arxiv   +1 more source

A vesicle bioreactor as a step toward an artificial cell assembly.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2004
An Escherichia coli cell-free expression system is encapsulated in a phospholipid vesicle to build a cell-like bioreactor. Large unilamellar vesicles containing extracts are produced in an oil-extract emulsion.
V. Noireaux, A. Libchaber
semanticscholar   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Membrane Vesicle Release in Bacteria, Eukaryotes, and Archaea: a Conserved yet Underappreciated Aspect of Microbial Life

open access: yesInfection and Immunity, 2012
Interaction of microbes with their environment depends on features of the dynamic microbial surface throughout cell growth and division. Surface modifications, whether used to acquire nutrients, defend against other microbes, or resist the pressures of a
B. Deatherage, B. Cookson
semanticscholar   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Reproducible extracellular vesicle size and concentration determination with tunable resistive pulse sensing

open access: yesJournal of Extracellular Vesicles, 2014
Introduction The size of extracellular vesicles (EVs) can be determined with a tunable resistive pulse sensor (TRPS). Because the sensing pore diameter varies from pore to pore, the minimum detectable diameter also varies.
F. Coumans   +6 more
semanticscholar   +1 more source

Flocculation of vesicles

open access: yes, 2011
The flocculation of liposomes is theoretically studied. An expression for the flocculation activation energy is derived, accounting for the electrostatic and hydrophobic interactions as well as for the correlation area of floc-spots.
openaire   +2 more sources

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Unraveling How Antimicrobial Lipid Mixtures Disrupt Virus-Mimicking Lipid Vesicles: A QCM-D Study

open access: yesBiomimetics
Single-chain lipid amphiphiles such as fatty acids and monoglycerides are promising antimicrobial alternatives to replace industrial surfactants for membrane-enveloped pathogen inhibition.
Suji Moon   +3 more
doaj   +1 more source

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