Results 101 to 110 of about 411,930 (215)

Cooperative engulfment of nanoparticles by membranes and vesicles

open access: yesNew Journal of Physics
Cellular uptake and expulsion of nanoparticles and viruses often involves a substantial particle concentration at the cell membrane. These particles, many of which are distributed across the cell at relatively large distances, cooperate to enter or exit ...
Arash Bahrami, Amir H Bahrami
doaj   +1 more source

When Vesicles Mislead: A Rare Case of Massive Lymphangioma Circumscriptum of the Vulva

open access: yesJournal of Mid-Life Health
Background: Lymphangioma circumscriptum (LC) is a benign lymphatic malformation resulting from dilated lymphatic vessels in the skin and subcutaneous tissue. It commonly affects the chest, tongue, axilla, and oral cavity.
Lajya Devi Goyal   +2 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Dual membrane-spanning anti-sigma 2 controls OMV biogenesis and colonization fitness in Bacteroides thetaiotaomicron

open access: yesJournal of Bacteriology
Bacteroides spp. are gram-negative, gut commensals that shape the enteric landscape by producing outer membrane vesicles (OMVs) that degrade dietary fibers and traffic immunomodulatory biomolecules.
Evan J. Pardue   +8 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Stimuli‐Responsive Nanoplatforms: ZIF‐8‐Decorated Ferrocenyl Surfactant‐Based Vesicles for Synergistic Therapeutic Applications

open access: yesAdvanced Materials Interfaces
One of the most important issues in the design and preparation of drug delivery systems in the recent years is versatility which includes providing synergistic therapeutic effects and sustainability.
Emin Uysal   +5 more
doaj   +1 more source

Motor vesicles

open access: yesCurrent Biology, 1991
E M, Hedgecock, D H, Hall
openaire   +2 more sources

Synaptic vesicles [PDF]

open access: yesCurrent Biology, 2004
Tyler, William J, Murthy, Venkatesh N
openaire   +2 more sources

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