Results 101 to 110 of about 411,930 (215)
Cooperative engulfment of nanoparticles by membranes and vesicles
Cellular uptake and expulsion of nanoparticles and viruses often involves a substantial particle concentration at the cell membrane. These particles, many of which are distributed across the cell at relatively large distances, cooperate to enter or exit ...
Arash Bahrami, Amir H Bahrami
doaj +1 more source
When Vesicles Mislead: A Rare Case of Massive Lymphangioma Circumscriptum of the Vulva
Background: Lymphangioma circumscriptum (LC) is a benign lymphatic malformation resulting from dilated lymphatic vessels in the skin and subcutaneous tissue. It commonly affects the chest, tongue, axilla, and oral cavity.
Lajya Devi Goyal +2 more
doaj +1 more source
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Bacteroides spp. are gram-negative, gut commensals that shape the enteric landscape by producing outer membrane vesicles (OMVs) that degrade dietary fibers and traffic immunomodulatory biomolecules.
Evan J. Pardue +8 more
doaj +1 more source
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
One of the most important issues in the design and preparation of drug delivery systems in the recent years is versatility which includes providing synergistic therapeutic effects and sustainability.
Emin Uysal +5 more
doaj +1 more source

