Results 41 to 50 of about 679,023 (353)

Effect of Interactions Between Anionic Vesicles and a Cationic Terpolymer in Concentrated Solution Regime: Morphology and Size Changes of the Vesicular Particles [PDF]

علوم و تکنولوژی پلیمر, 2016
Interactions between polyelectrolytes and oppositely charged vesicular particles have many possible applications in drug delivery or gene therapy. Formation of vesicular structures by 2-(propylcarbamoyl) terephthalic acid heptaisobutyl POSS (POSS DCA) in
Farzad Lahootifard, Mohammad Imani, Ali Akbar Yousefi   +2 more
doaj   +1 more source

Model charged cylindrical nanopore in a colloidal dispersion: charge reversal, overcharging and double overcharging [PDF]

, 2017
Using the hypernetted-chain/mean spherical approximation (HNC/MSA) integral equations we study the electrical double layer inside and outside a model charged cylindrical vesicle (nanopore) immersed into a primitive model macroions solution, so that the ...
González-Tovar, E., Lozada-Cassou, M.
core   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

5‐Fluorouracil treatment represses pseudouridine‐containing miRNA export into extracellular vesicles

Journal of Extracellular Biology
5‐Fluorouracil (5‐FU) has been used for chemotherapy for colorectal and other cancers for over 50 years. The prevailing view of its mechanism of action is inhibition of thymidine synthase leading to defects in DNA replication and repair. However, 5‐FU is
Shimian Qu, Hannah M. Nelson, Xiao Liu, Yu Wang, Elizabeth M. Semler, Danielle L. Michell, Clark Massick, Jeffrey L. Franklin, John Karijolich, Alissa M. Weaver, Robert J. Coffey, Qi Liu, Kasey C. Vickers, James G. Patton   +13 more
doaj   +1 more source

Revisiting the Role of Clathrin-Mediated Endoytosis in Synaptic Vesicle Recycling

Frontiers in Cellular Neuroscience, 2018
Without robust mechanisms to efficiently form new synaptic vesicles (SVs), the tens to hundreds of SVs typically present at the neuronal synapse would be rapidly used up, even at modest levels of neuronal activity.
Ira Milosevic
doaj   +1 more source

Charge-Reversal Instability in Mixed Bilayer Vesicles

, 2000
Bilayer vesicles form readily from mixtures of charged and neutral surfactants. When such a mixed vesicle binds an oppositely-charged object, its membrane partially demixes: the adhesion zone recruits more charged surfactants from the rest of the ...
A. D. Dinsmore, E. J. W. Vervey, H. Aranda-Espinosa, H. Totsuji, I. Rouzina, J. N. Israelachvili, J. Nardi, J. Nardi, J. Nardi, L. D. Landau, L. Guldbrand, L. Ramos, P. Attard, Philip Nelson, R. B. Gennis, R. Kjellander, R. Kjellander, R. Williams, S. A. Safran, S. H. Behrens, S. Hachisu, V. A. Parsegian, V. I. Perel, W. B. Russel, Yi Chen   +24 more
core   +2 more sources

Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion. [PDF]

, 2012
The molecular underpinnings of synaptic vesicle fusion for fast neurotransmitter release are still unclear. Here, we used a single vesicle-vesicle system with reconstituted SNARE and synaptotagmin-1 proteoliposomes to decipher the temporal sequence of ...
Brunger, Axel T, Chu, Steven, Cipriano, Daniel J, Diao, Jiajie, Grob, Patricia, Kyoung, Minjoung, Nguyen, Amie, Nogales, Eva, Padolina, Mark, Shah, Ankita, Shah, Sachi, Srivastava, Ankita, Vrljic, Marija, Zhang, Yunxiang   +13 more
core   +1 more source

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

Law of corresponding states for osmotic swelling of vesicles

, 2012
As solute molecules permeate into a vesicle due to a concentration difference across its membrane, the vesicle swells through osmosis. The swelling can be divided into two stages: (a) an "ironing" stage, where the volume-to-area ratio of the vesicle ...
Angelova, Diamant, Dimova, Dordas, Döbereiner, Emir Haleva, Evans, Farago, Farago, Fournier, Haim Diamant, Haleva, Haleva, Heinrich, Helfrich, Krasteva, Linke, Litster, Mally, Marsh, Milner, Mui, Orbach, Patel, Paula, Peterlin, Peterlin, Pocivavsek, Primož Peterlin, Schmid, Seifert, Vesna Arrigler, Vitkova   +32 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source