Results 51 to 60 of about 503,736 (302)
Clathrin-independent pathways do not contribute significantly to endocytic flux
eLife, 2014 Several different endocytic pathways have been proposed to function in mammalian cells. Clathrin-coated pits are well defined, but the identity, mechanism and function of alternative pathways have been controversial.
Vassilis Bitsikas +2 more
doaj +1 more source
GENETICSAbstract Extracellular vesicles (EVs) encompass a diverse array of membrane-bound organelles released outside cells in response to developmental and physiological cell needs. EVs play important roles in remodeling the shape and content of differentiating cells and can rescue damaged cells from toxic or dysfunctional content. EVs can send
Juan Wang, Maureen M Barr, Ann M Wehman
openaire +4 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Magnetic resonance investigations of phase separation in vesicle-polymer mixtures
, 2019 Vesicle dispersions are used in consumer products, cosmetics and food. Frequently, non-adsorbing polymer is added to dispersions to enhance properties, such as, dispensibility.
Thompson, Emma Sian
core +4 more sources
Analysis of molecular mechanisms of extracellular vesicle formation and development of technologies for profiling extracellular vesicle heterogeneity [PDF]
岩手大学博士（学術）原著論文 Maeda, K., Goto, S., Miura, K., Saito, K., Morita, E. The Incorporation of Extracellular Vesicle Markers Varies Among Vesicles with Distinct Surface Charges The Journal of Biochemistry 175 (3), 299-312, 2024doctoral ...
前⽥, 昂樹
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Neurotransmitter depletion by bafilomycin is promoted by vesicle turnover.
, 2007 PC is in NPA laboratory from 2005Accumulation of neurotransmitter into synaptic vesicles is powered by the vacuolar proton ATPase. We show here that, in brain slices, application of the H(+)-ATPase inhibitors bafilomycin or concanamycin does not ...
Cavelier, Pauline, Attwell, David
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
A Fusion–Growth Protocell Model Based on Vesicle Interactions with Pyrite Particles
MoleculesProtocell models play a pivotal role in the exploration of the origin of life. Vesicles are one type of protocell model that have attracted much attention.
Dong Guo +5 more
doaj +1 more source