Results 31 to 40 of about 1,227,442 (389)
Fusion Pore Diameter Regulation by Cations Modulating Local Membrane Anisotropy
The Scientific World Journal, 2012 The fusion pore is an aqueous channel that is formed upon the fusion of the vesicle membrane with the plasma membrane. Once the pore is open, it may close again (transient fusion) or widen completely (full fusion) to permit vesicle cargo discharge. While
Doron Kabaso +5 more
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Temporal Separation of Vesicle Release from Vesicle Fusion during Exocytosis [PDF]
Journal of Biological Chemistry, 2002 During exocytosis, vesicles in secretory cells fuse with the cellular membrane and release their contents in a Ca2+-dependent process. Release occurs initially through a fusion pore, and its rate is limited by the dissociation of the matrix-associated contents.
Kevin P. Troyer, R. Mark Wightman
openalex +4 more sources
Munc18-1: sequential interactions with the fusion machinery stimulate vesicle docking and priming [PDF]
, 2007 Exocytosis of secretory or synaptic vesicles is executed by a mechanism including the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins.
Gulyás-Kovács, A. +7 more
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Synaptotagmin 1 clamps synaptic vesicle fusion in mammalian neurons independent of complexin
Nature Communications, 2019 Synaptic vesicle (SV) exocytosis is mediated by SNARE proteins. Reconstituted SNAREs are constitutively active, so a major focus has been to identify fusion clamps that regulate their activity in synapses: the primary candidates are synaptotagmin (syt) 1
Nicholas A. Courtney +3 more
semanticscholar +1 more source
Alamethicin-mediated fusion of lecithin vesicles. [PDF]
Proceedings of the National Academy of Sciences, 1975 It was recently shown that alamethicin greatly facilitates the fusion of small, sonicated, lecithin bilayer vesicles. In the present work the details of this fusion process have been followed by monitoring the inner and outer choline methyl signals separately by proton magnetic resonance spectroscopy.
Lau, Arthur L. Y., Chan, Sunney I.
openaire +4 more sources
Cells, 2018 Vesicle fusion is a fundamental cell biological process similar from yeasts to humans. For secretory vesicles, swelling is considered a step required for the expulsion of intravesicular content.
Mariangela Centrone +12 more
doaj +1 more source
Actin and Myosin in Non-Neuronal Exocytosis
Cells, 2020 Cellular secretion depends on exocytosis of secretory vesicles and discharge of vesicle contents. Actin and myosin are essential for pre-fusion and post-fusion stages of exocytosis.
Pika Miklavc, Manfred Frick
doaj +1 more source
Intrinsic tethering activity of endosomal Rab proteins. [PDF]
, 2011 Rab small G proteins control membrane trafficking events required for many processes including secretion, lipid metabolism, antigen presentation and growth factor signaling.
Brett, Christopher L +6 more
core +3 more sources
Calcium dependence of neurotransmitter release at a high fidelity synapse
eLife, 2021 The Ca2+-dependence of the priming, fusion, and replenishment of synaptic vesicles are fundamental parameters controlling neurotransmitter release and synaptic plasticity.
Abdelmoneim Eshra +3 more
doaj +1 more source
Membrane fusion mediated by ricin and viscumin [PDF]
, 1998 The ribosome inactivating plant proteins (RIPs) ricin and viscumin but not Ricinus communis agglutinin are able induce vesicle–vesicle fusion. A model is suggested in which the toxicity of the RIPs is partially determined by their fusogenicity.
Peter Pohl +39 more
core +1 more source