Results 91 to 100 of about 1,068,905 (341)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Imaging optical thicknesses and separation distances of phospholipid vesicles at solid surfaces [PDF]

open access: yes, 1992
We present the application of reflection interference contrast microscopy (RICM) (1) to map the optical density of supported bilayers and vesicles and (2) to image the contact profile of phospholipid vesicles at surfaces.
Rädler, Joachim O., Sackmann, E.
core   +3 more sources

Diet, commensal microbiota‐derived extracellular vesicles, and host immunity [PDF]

open access: hybrid, 2023
Jemma Taitz   +6 more
openalex   +1 more source

Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes

open access: yesScience, 2018
Defense cargo shuttles in vesicles Plants can use small RNAs (sRNAs) to interfere with virulence factor gene expression in pathogens. Cai et al. show that the small mustard plant Arabidopsis shuttles defensive sRNAs into the necrotrophic fungus Botrytis ...
Qiang Cai   +7 more
semanticscholar   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

open access: yesMolecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo   +6 more
wiley   +1 more source

Characteristic spatial scale of vesicle pair interactions in a plane linear flow

open access: yes, 2012
We report the experimental studies on interaction of two vesicles trapped in a microfluidic analog of four-roll mill, where a plane linear flow is realized.
Eldad Afik   +4 more
core   +3 more sources

Minimal Bending Energies of Bilayer Polyhedra [PDF]

open access: yes, 2010
Motivated by recent experiments on bilayer polyhedra composed of amphiphilic molecules, we study the elastic bending energies of bilayer vesicles forming polyhedral shapes.
Christoph A. Haselwandter   +5 more
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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