Results 121 to 130 of about 1,068,905 (341)

Increased Hematopoietic Extracellular RNAs and Vesicles in the Lung during Allergic Airway Responses. [PDF]

, 2019
Extracellular RNAs (exRNAs) can be released by numerous cell types in vitro, are often protected within vesicles, and can modify recipient cell function. To determine how the composition and cellular sources of exRNAs and the extracellular vesicles (EVs)
Ansel, K Mark, Chiou, Ni-Ting, Gray, Carleigh J, Happ, Hannah C, Hesse, Laura E, Mar, Darryl J, Pua, Heather H   +6 more
core   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

Renal epithelial cells can release ATP by vesicular fusion

Frontiers in Physiology, 2013
Renal epithelial cells have the ability to release nucleotides as paracrine factors. In the intercalated cells of the collecting duct, ATP is released by connexin30 (cx30), which is selectively expressed in this cell type.
Randi G Bjaelde, Sigrid S Arnadottir, Morten T Overgaard, Jens eLeipziger, Helle A Praetorius   +4 more
doaj   +1 more source

Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications

Journal of Extracellular Vesicles, 2019
Small extracellular vesicles (sEVs) from mesenchymal stromal/stem cells (MSCs) are transiting rapidly towards clinical applications. However, discrepancies and controversies about the biology, functions, and potency of MSC-sEVs have arisen due to several
K. Witwer, B. W. van Balkom, S. Bruno, A. Choo, M. Dominici, M. Gimona, A. Hill, D. D. de Kleijn, M. Koh, R. C. Lai, S. Mitsialis, L. Ortiz, E. Rohde, Takashi Asada, W. Toh, D. Weiss, Lei Zheng, B. Giebel, S. Lim   +18 more
semanticscholar   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

Endoplasmic Reticulum: The Favorite Intracellular Niche for Viral Replication and Assembly

Viruses, 2016
The endoplasmic reticulum (ER) is the largest intracellular organelle. It forms a complex network of continuous sheets and tubules, extending from the nuclear envelope (NE) to the plasma membrane.
Inés Romero-Brey, Ralf Bartenschlager
doaj   +1 more source

Extracellular vesicles-mediated intercellular communication: roles in the tumor microenvironment and anti-cancer drug resistance

Molecular Cancer, 2019
The tumor microenvironment represents a complex network, in which tumor cells not only communicate with each other but also with stromal and immune cells.
Selma Maacha, A. Bhat, Lizandra Jimenez, A. Raza, Mohammad Haris, S. Uddin, J. Grivel   +6 more
semanticscholar   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Nanovesicles-Mediated Drug Delivery for Oral Bioavailability Enhancement

International Journal of Nanomedicine, 2022
Yuehong Ren,1,* Linghui Nie,2,* Shiping Zhu,3 Xingwang Zhang1 1Department of Pharmaceutics, College of Pharmacy, Jinan University, Guangzhou, People’s Republic of China; 2ASD Medical Rehabilitation Center, the Second People’s Hospital of ...
Ren Y, Nie L, Zhu S, Zhang X
doaj  

Responsive Polydiacetylene Vesicles for Biosensing Microorganisms

Sensors, 2018
Polydiacetylene (PDA) inserted in films or in vesicles has received increasing attention due to its property to undergo a blue-to-red colorimetric transition along with a change from non-fluorescent to fluorescent upon application of various stimuli.
Estelle Lebègue, Carole Farre, Catherine Jose, Joelle Saulnier, Florence Lagarde, Yves Chevalier, Carole Chaix, Nicole Jaffrezic-Renault   +7 more
doaj   +1 more source