Results 231 to 240 of about 1,068,905 (341)

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

Advanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li, Elliya Park, Chunsheng He, Azhar Z. Abbasi, Pei Zhi, Paul E. Fraser, Andrew M. Rauth, Jeffery T. Henderson, Xiao Yu Wu   +8 more
wiley   +1 more source

Dynamic Shape Modulation of Deflated and Adhered Lipid Vesicles. [PDF]

J Am Chem Soc
Wolfisberg G, Agudo-Canalejo J, Bittmann PC, Dufresne ER, Style RW, Rebane AA.   +5 more
europepmc   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Faculty Opinions recommendation of v-SNARE composition distinguishes synaptic vesicle pools.

, 2012
Erwin Neher
openalex   +2 more sources

Rotation of Vibrio fischeri Flagella Produces Outer Membrane Vesicles That Induce Host Development [PDF]

, 2016
Marie‐Stéphanie Aschtgen, Jonathan B. Lynch, Eric J. Koch, Julia Schwartzman, Margaret McFall‐Ngai, Edward G. Ruby   +5 more
openalex   +1 more source

Native and bioengineered extracellular vesicles for cardiovascular therapeutics

Nature Reviews Cardiology, 2020
R. D. de Abreu, H. Fernandes, P. A. da Costa Martins, S. Sahoo, C. Emanueli, L. Ferreira   +5 more
semanticscholar   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Impact of Lipid Bilayer Composition and Physicochemical Properties on Constitution of a Transmembrane Helical Peptide into Exosome-Mimetic Vesicles. [PDF]

Mol Pharm
Tsutsumi S, Takechi-Haraya Y, Abe Y, Kawakami K.   +3 more
europepmc   +1 more source

Androgen deficiency-induced loss of Lactobacillus salivarius extracellular vesicles is associated with the pathogenesis of osteoporosis

Wenjun Zhang, Jian Xie, Zhuoya Wang, Yuchun Zhong, Li Liu, Junping Liu, Wenming Zhang, Yecan Pi, Furui Tang, Zehong Liu, Yinjin Shao, Liu Tian, Cihua Zheng, Jun Luo   +13 more
openalex   +1 more source

Chromatin and extracellular vesicle associated sperm RNAs [PDF]

, 2015
Graham D. Johnson, Paula M. Mackie, Meritxell Jodar, Sergey I. Moskovtsev, Stephen A. Krawetz   +4 more
openalex   +1 more source