Results 271 to 280 of about 1,068,905 (341)

Single-particle analysis of small extracellular vesicles from human follicular fluid unveils immunomodulatory PD-L1⁺ subpopulations and potentially fertility biomarkers. [PDF]

PeerJ
Bortot B, Di Florio R, Zito G, Valle F, Brucale M, Ricci G, Vigano P, Biffi S.   +7 more
europepmc   +1 more source

Magnetic Resonance Imaging‐Based Quantification of Endosomal Escape Using Iron Oxide Nanoparticle‐Loaded Lipid Nanoparticles

Advanced Healthcare Materials, EarlyView.
The therapeutic efficacy of lipid nanoparticle(LNP)‐based drugs depends on endosomal escape. However, few methods are available for quantifying the efficiency of endosomal escape in vivo. Herein, a novel method for quantifying the endosomal escape efficiency index using magnetic resonance imaging is introduced.
Somin Lee, Jeongbin Park, Han Na Jung, Shengjun Li, Zhijun Lin, Hyung‐Jun Im   +5 more
wiley   +1 more source

Programmable DNA shell scaffolds for directional membrane budding. [PDF]

Nat Commun
Pinner MT, Dietz H.
europepmc   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Diagnostic and prognostic roles of circulating EVs circ_PPAPDC1A in ICIs resistance in NSCLC. [PDF]

NPJ Precis Oncol
Zou FW, Tang YF, Zhang LY, Xu S, Yang SZ, Li WY, Liu ZH.   +6 more
europepmc   +1 more source

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

Advanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor, Giuseppe Longobardi, Or Kandli, Anne Krinsky, Opal Avramoff, Anshika Katyal, Koren Salomon, Adan Miari, Dana Venkert, Tania T. Barnatan, América García Alvarado, Shahar Greenberg, Ronit Satchi‐Fainaro   +12 more
wiley   +1 more source

Dimensions, stability, and deformability of DOPC-cholesterol giant unilamellar vesicles formed by droplet transfer. [PDF]

Open Res Eur
Roberti E, Petrocelli EL, Cecchi D, Palagi S.   +3 more
europepmc   +1 more source

Development of a Synthetic 3D Platform for Compartmentalized Kidney In Vitro Disease Modeling

Advanced Healthcare Materials, EarlyView.
A fully synthetic, compartmentalized 3D kidney disease model is introduced. The kidney model combines a PEG‐based hydrogel matrix with anisotropic, enzymatically degradable rod‐shaped microgels to spatially arrange a triple co‐culture of key renal epithelial, endothelial, and fibroblast cells.
Ninon Möhl, Daphne Bouwens, Johanna Abele, Aline Hans, Tanja Topic, Daniel Günther, Jitske Jansen, Rafael Kramann, Laura De Laporte   +8 more
wiley   +1 more source

Extracellular vesicles in cardiovascular diseases: pathogenic mediators, diagnostic tools, and therapeutic vectors. [PDF]

Front Cardiovasc Med
Li T, Wang W, Qin Z, Chen Y, Zhu K, Liu H, Sun J, Zhong H.   +7 more
europepmc   +1 more source

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis.

Cancer Cell, 2016
A. Becker, B. K. Thakur, Joshua M. Weiss, Han Sang Kim, H. Peinado, D. Lyden   +5 more
semanticscholar   +1 more source