Results 21 to 30 of about 149,274 (318)

A VSV-based assay quantifies coronavirus Mpro/3CLpro/Nsp5 main protease activity and chemical inhibition

open access: yesCommunications Biology, 2022
A vesicular stomatitis virus (VSV)-based assay enables high-throughput screening for small molecular protease inhibitors that can block viral proteases, like the Mpro/3CLpro/Nsp5 in SARS-CoV-2.
Emmanuel Heilmann   +7 more
doaj   +1 more source

Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]

open access: yes, 2015
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam   +3 more
core   +3 more sources

Effect of Recombinant Vesicular Stomatitis Virus–Zaire Ebola Virus Vaccination on Ebola Virus Disease Illness and Death, Democratic Republic of the Congo

open access: yesEmerging Infectious Diseases, 2022
We conducted a retrospective cohort study to assess the effect vaccination with the live-attenuated recombinant vesicular stomatitis virus–Zaire Ebola virus vaccine had on deaths among patients who had laboratory-confirmed Ebola virus disease (EVD).
Neil Rupani   +12 more
doaj   +1 more source

Viroses confundíveis com febre aftosa Viral diseases to be differentiated from foot-and-mouth disease

open access: yesCiência Rural, 1996
Revisam-se as doenças que devem ser consideradas no diagnóstico diferencial de febre aftosa. Dentre as doenças vesiculares ou erosivas, descrevem-se os principais aspectos relacionados ao diagnóstico da estomatite vesicular, diarréia viral bovina, febre ...
Franklin Riet-Correa   +3 more
doaj   +1 more source

Examination of vesicular stomatitis virus-induced morphology changes in individual Vero cells by QMod microscopy

open access: yesBioTechniques, 2020
Viral infection of cultured cells induces changes in the biophysical characteristics of the affected cells. Advanced microscopic cameras such as Ovizio’s QMod, coupled with the appropriate software, can measure a variety of characteristics on a per-cell ...
Isabel Scholz   +2 more
doaj   +1 more source

Atomic model of vesicular stomatitis virus and mechanism of assembly

open access: yesNature Communications, 2022
Zhou and Si et al. used cryogenic electron microscopy and tomography to delineate the molecular interactions among genomic RNA, nucleocapsid protein, matrix protein and glycoprotein in vesicular stomatitis virus and suggest a model of assembly.
Kang Zhou   +5 more
doaj   +1 more source

Aptamer-facilitated Protection of Oncolytic Virus from Neutralizing Antibodies

open access: yesMolecular Therapy: Nucleic Acids, 2014
Oncolytic viruses promise to significantly improve current cancer treatments through their tumor-selective replication and multimodal attack against cancer cells.
Darija Muharemagic   +6 more
doaj   +1 more source

Autophagy gene activity may act as a key factor for sensitivity of tumor cells to oncolytic vesicular stomatitis virus [PDF]

open access: yes, 2016
Background: Beclin1 is an important, primary molecule for autophagy. Objectives: It is suggested that the control of the autophagy path increases the sensitivity of tumor cells to VSV.
Arefian, E.   +3 more
core   +2 more sources

Nail changes secondary to hand-foot-mouth disease

open access: yesThe Turkish Journal of Pediatrics, 2016
Hand-foot-mouth disease (HFMD) is a viral disease that is characterized by palmoplantar vesicular eruption and erosive stomatitis. Beau's line and onychomadesis can be observed as late findings following HFMD due to arrest in nail matrix. We aimed
Nebahat Demet Akpolat, Nezih Karaca
doaj   +1 more source

Single virus fingerprinting by widefield interferometric defocus-enhanced mid-infrared photothermal microscopy

open access: yesNature Communications, 2023
Clinical identification and fundamental study of viruses rely on the detection of viral proteins or viral nucleic acids. Yet, amplification-based and antigen-based methods are not able to provide precise compositional information of individual virions ...
Qing Xia   +8 more
doaj   +1 more source

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