Results 31 to 40 of about 63,207 (233)

Frequency analysis of cytolytic T lymphocyte precursors (CTL-P) generated in vivo during lethal rabies infection of mice. II. Rabies virus genus specificity of CTL-P [PDF]

, 1984
Cytolytic T lymphocyte precursors (CTL-P) were sensitized in vivo by intraplantar infection of C57BL/6 mice with a lethal dose of rabies virus, strain ERA (ERA).
Aden, Baer, Berke, Cox, Fazekas De, Grimm, Koprowski, Minato, Reddehase, Reddehase, Reddehase, Rosenthal, Rosenthal, Schneider, Sethi, Shope, Shope, Stoker, Taswell, Wiktor, Wiktor, Zinkernagel, Zinkernagel   +22 more
core   +1 more source

Helical Virus Structure: The Case of the Rhabdovirus Bullet

Viruses, 2010
Commentary on Ge, P.; Tsao, J.; Schein, S.; Green, T.J.; Luo, M.; Zhou, Z.H. Cryo-EM model of the bullet-shaped vesicular stomatitis virus. Science 2010, 327, 689-693.
Jay C. Brown, William W. Newcomb, Gail W. Wertz   +2 more
doaj   +1 more source

Conformational spread as a mechanism for cooperativity in the bacterial flagellar switch [PDF]

, 2010
The bacterial flagellar switch that controls the direction of flagellar rotation during chemotaxis has a highly cooperative response. This has previously been understood in terms of the classic two-state, concerted model of allosteric regulation.
F. Bai, R. W. Branch, D. V. Nicolau, T. Pilizota, B. C. Steel, P. K. Maini, R. M. Berry, Monod, Duke, Duke, Changeux, Sowa, Cluzel, Bray, Turner, Alon, Kudo, Block, Scharf, Korobkova, Sowa, Ryu, Korobkova, Lapidus, Block, van Albada, Yuan, Karpen, Dyer, Van Way   +29 more
core   +3 more sources

A dose-dependent plasma signature of the safety and immunogenicity of the rVSV-Ebola vaccine in Europe and Africa. [PDF]

, 2017
The 2014-2015 Ebola epidemic affected several African countries, claiming more than 11,000 lives and leaving thousands with ongoing sequelae. Safe and effective vaccines could prevent or limit future outbreaks.
Agnandji, ST, Brosnahan, J, Combescure, C, Dayer, J-A, Grillet, S, Haks, MC, Harandi, AM, Huttner, A, Kaiser, L, Kremsner, PG, Medaglini, D, Modoux, C, Monath, T, Ottenhoff, THM, Quinten, E, Roux-Lombard, P, Siegrist, C-A, VEBCON and VSV-EBOVAC Consortia   +17 more
core   +2 more sources

Measuring Genetic Robustness in Vesicular Stomatitis Virus

Bio-Protocol, 2014
Genetic robustness is the ability of a genome to incorporate mutations with the result of no fitness changes. Thus, more robust viruses have an increased neutral mutation rate.
Isabel Novella
doaj   +1 more source

Eradication of Swine Vesicular Disease in Italy

Viruses, 2020
Swine vesicular disease (SVD) is a contagious viral disease of pigs clinically indistinguishable from other vesicular diseases, such as foot and mouth disease, vesicular stomatitis, vesicular exanthema of swine, and idiopathic vesicular disease. In Italy,
Marco Tamba, Francesco Plasmati, Emiliana Brocchi, Luigi Ruocco   +3 more
doaj   +1 more source

Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy

Nature Communications, 2021
Oncolytic viruses, such as vesicular stomatitis virus (VSV), are a promising class of cancer therapeutics. Here the authors report that a mutation in the CSDE1 gene renders cancer cells resistant to VSV replication and oncolysis, but a mutation-derived ...
Timothy Kottke, Jason Tonne, Laura Evgin, Christopher B. Driscoll, Jacob van Vloten, Victoria A. Jennings, Amanda L. Huff, Brady Zell, Jill M. Thompson, Phonphimon Wongthida, Jose Pulido, Matthew R. Schuelke, Adel Samson, Peter Selby, Elizabeth Ilett, Mark McNiven, Lewis R. Roberts, Mitesh J. Borad, Hardev Pandha, Kevin Harrington, Alan Melcher, Richard G. Vile   +21 more
doaj   +1 more source

Cytokine-modified VSV is attenuated for neural pathology, but is both highly immunogenic and oncolytic [PDF]

, 2009
Vesicular stomatitis virus (VSV), an enveloped, nonsegmented, negative-stranded RNA virus, is being tested by several laboratories as an antitumor agent.
Bidula, Sarah M, Jensen, Troels M, Miller, James, Reiss, Carol Shoshkes   +3 more
core   +1 more source

Tamoxifen Protects from Vesicular Stomatitis Virus Infection

Pharmaceuticals, 2019
Background: Tamoxifen (TAM) is an estrogen-receptor antagonist, widely used in the adjuvant treatment of early stage estrogen-sensitive breast cancer.
Lamin B. Cham, Sarah-Kim Friedrich, Tom Adomati, Hilal Bhat, Maximilian Schiller, Michael Bergerhausen, Thamer Hamdan, Fanghui Li, Yara Maria Machlah, Murtaza Ali, Vikas Duhan, Karl Sebastian Lang, Justa Friebus-Kardash, Judith Bezgovsek   +13 more
doaj   +1 more source

Bat Employs a Conserved MDA5 Gene to Trigger Antiviral Innate Immune Responses

Frontiers in Immunology, 2022
Bats are important hosts for various zoonotic viral diseases. However, they rarely show signs of disease infection with such viruses. As the first line for virus control, the innate immune system of bats attracted our full attention.
Jie Wang, Zhenyu Lin, Qiuju Liu, Feiyu Fu, Zhaofei Wang, Jingjiao Ma, Hengan Wang, Yaxian Yan, Yuqiang Cheng, Jianhe Sun   +9 more
doaj   +1 more source